Arsenor
Arsenor Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Arsenor is a brand name. Its generic name is Apremilast.
Aprmielast Introduction
Aprmielast is a prescription oral medication used to treat psoriatic arthritis and moderate to severe plaque psoriasis. It is an inhibitor of phosphodiesterase 4 (PDE4), an enzyme which plays a role in inflammation and immune response. Aprmielast is available in tablet form and is taken once a day.
Uses For
Aprmielast is indicated for the treatment of moderate to severe plaque psoriasis in adults and for the treatment of adults with active psoriatic arthritis. Aprmielast is not indicated for the treatment of other forms of arthritis.
Mechanism of Action
Aprmielast works by inhibiting the activity of the enzyme phosphodiesterase 4 (PDE4), which is involved inflammation. By blocking PDE4 activity, Aprmielast helps to reduce inflammation and reduce the symptoms associated with plaque psoriasis and psoriatic arthritis.
How Long Does it Take to Work?
The effect of Aprmielast can be seen within 4 to 6 weeks of treatment. Maximum effectiveness may not be seen until 12 weeks or longer. May take up to 16 weeks or longer to achieve maximum benefit.
Absorption
Aprmielast is rapidly absorbed after oral dosing. Peak concentrations are generally reached 2-3 hours after administration.
Route of Elimination
Aprmielast is eliminated from the body via renal excretion. About 65% of the absorbed dose is excreted unchanged in the urine.
Dosage
The recommended dosage of Aprmielast is 30 mg taken twice daily. This dosage can be increased to 60 mg twice daily if needed. Aprmielast should be taken with food in order to reduce the chance of stomach upset or diarrhea.
Administration
Aprmielast tablets should be swallowed whole with a glass of water. They should not be chewed, crushed, or broken. It is important to take Aprmielast exactly as directed by your healthcare provider.
Side Effects
Some common side effects of Aprmielast may include nausea, headache, diarrhea, abdominal pain, and fatigue. More serious side effects may include depression and suicidal thoughts.
Toxicity
Aprmielast has not been found to be toxic in clinical trials. However, patients should be monitored for serious side effects such as depression and suicidal ideation.
Precautions
Aprmielast should be used with caution in patients with a history of depression or other mental health conditions. It is important to discuss any concerns with your doctor before starting Aprmielast.
Interactions
Aprmielast may interact with certain prescription or over-the-counter medications, so it is important to discuss any potential drug interactions with your doctor before using Aprmielast.
Disease Interactions
Aprmielast may interact with certain diseases, such as depression or other mental health conditions. It is important to discuss any existing medical conditions with your doctor before using Aprmielast.
Drug Interactions
Aprmielast may interact with certain drugs. Be sure to tell your doctor about any other medications you may be taking before using Aprmielast.
Food Interactions
Foods that contain high-fat content may decrease the amount of Aprmielast that is absorbed. It is therefore recommended to avoid high-fat foods such as French fries when taking Aprmielast.
Pregnancy Use
Aprmielast has not been studied in pregnant women and therefore is not recommended for use in pregnant women. Women should speak to their doctor before taking Aprmielast if they are pregnant or planning to become pregnant.
Lactation Use
It is not known if Aprmielast is excreted in breast milk. Therefore, Aprmielast should not be used while breastfeeding.
Acute Overdose
If an overdose of Aprmielast is suspected, contact the Poison Control Center at 1-800-222-1222. Symptoms of overdose may include nausea, vomiting, abdominal pain, and diarrhea.
Contraindication
Aprmielast is contraindicated in patients with a known hypersensitivity to the drug, as well as those with severe liver impairment.
Use Directions
Aprmielast should be taken exactly as prescribed by your healthcare provider. It is important to take Aprmielast with food in order to reduce the chance of stomach upset or diarrhea.
Storage Conditions
Aprmielast should be stored at room temperature, away from light and moisture. It should not be kept in the refrigerator.
Volume of Distribution
The volume of distribution for Aprmielast is not known.
Half Life
The half life for Aprmielast is approximately 13 hours.
Clearance
The clearance of Aprmielast is not known.
Here you find in details version of Arsenor
Some Frequently Asked Questions About Arsenor
What is Arsenor?
Arsenor is an oral prescription medicine used for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate. It is a phosphodiesterase 4 (PDE-4) inhibitor.
What is the mechanism of action for Arsenor?
Arsenor works by inhibiting the release of pro-inflammatory mediators involved in plaque psoriasis. It also serves to inhibit T-lymphocyte activation, which helps reduce the inflammatory response.
What are the side effects of Arsenor?
The most common side effects associated with Arsenor include nausea, headache, diarrhoea, upper respiratory tract infection, abdominal pain, fatigue, nasopharyngitis and depression.
Is Arsenor approved for the treatment of psoriatic arthritis?
Yes, Arsenor is approved for the treatment of psoriatic arthritis in addition to plaque psoriasis.
How long does a treatment course of Arsenor last?
The duration of treatment with Arsenor depends on a variety of factors, including the severity of the condition, the response to treatment, and other concurrent medications. Generally, it is recommended that a patient remain on the therapy for at least 3 to 6 months before a proper assessment can be made.
What is the recommended dosage for Arsenor?
The recommended dosage of Arsenor is 30mg taken orally twice daily with or without food.
Is Arsenor considered safe?
Yes, Arsenor has been studied extensively in clinical trials and has been approved by the FDA. It is considered a safe and effective treatment for plaque psoriasis and psoriatic arthritis.
Can Arsenor be used in combination with other medications?
Yes, Arsenor can be used in combination with other medications such as topical corticosteroids and vitamin D derivatives for the treatment of plaque psoriasis.
Is Arsenor effective in treating psoriasis?
Yes, Arsenor has been shown to be effective in treating plaque psoriasis in clinical trials. Up to 45% of patients treated with Arsenor achieved at least a 75% improvement in their symptoms, compared to 25% of patients treated with placebo.
What is the typical duration of treatment with Arsenor?
The treatment duration of Arsenor depends on individual patient factors as described above. Generally, it is recommended that treatment is continued until there is a significant improvement in the symptoms and signs of the disease. Treatment should be continued until any disease flare-ups are under control.
Does Arsenor cause any serious side effects?
Arsenor has been studied extensively in clinical trials and is generally considered to be well-tolerated. However, there may be serious side effects associated with Arsenor, such as depression, increased risk of infections, and liver problems. Please consult with your doctor if you have any concerns or questions.
Is Arsenor a safe option for long-term management of psoriasis?
Yes, Arsenor has been studied extensively in clinical trials and is generally considered to be safe and well-tolerated for long-term use. However, it is important to note that the potential risks and side effects should be discussed with your doctor before starting treatment.
Does Arsenor interact with other medications?
Yes, Arsenor may interact with certain medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and anticoagulants. It is important to discuss any medications you are currently taking with your doctor before starting treatment with Arsenor.
How long does it take for Arsenor to start working?
The effects of Arsenor may vary from person to person. Generally, it can take up to 12 weeks for the effects of Arsenor to be seen. If no significant improvement is seen after this time period, your doctor may suggest a change in treatment.
What is the cost of Arsenor?
The cost of Arsenor can vary depending on a variety of factors, including insurance coverage. It is important to speak to your doctor and insurance provider to determine the exact cost of your treatment.
Can Arsenor be used during pregnancy?
No, Arsenor is not recommended for use during pregnancy. Animal studies suggest that there may be risks to the fetus, so it is important to discuss any pregnancy or plans for pregnancy with your doctor before starting treatment.
How should Arsenor be stored?
Arsenor should be stored in a cool, dry place and away from direct light. It should also be kept out of reach of children.
Can I donate blood while taking Arsenor?
It is recommended that you do not donate blood while taking Arsenor due to the potential for the drug to be passed to other individuals through the use of donated blood.
Is Arsenor available in generic form?
No, Arsenor is not currently available in generic form.
Can Arsenor be taken with food?
Yes, Arsenor can be taken with food.
Does Arsenor help with itching from psoriasis?
Yes, Arsenor has been shown to be effective in reducing itching associated with psoriasis.
Does Arsenor cause weight gain?
Arsenor has not been shown to be associated with weight gain in clinical trials. However, it is important to discuss any changes in weight with your doctor.
Is Arsenor covered by insurance?
Yes, Arsenor is typically covered by most insurance plans. It is important to check with your insurance provider to determine specifics of your coverage.
How should Arsenor be taken?
Arsenor should be taken orally twice daily with or without food. It is important to take the medicine as prescribed and not to increase or decrease the dose without consulting your doctor.
Is Arsenor safe for children?
Arsenor is not recommended for use in children. It is important to consult with your doctor before starting any medication for children.
Does Arsenor cause hair loss?
No, Arsenor has not been shown to cause hair loss in clinical trials.
Can Arsenor be used in combination with topical medications?
Yes, Arsenor can be used in combination with topical medications such as corticosteroids and vitamin D derivatives.
What should I do if I miss a dose of Arsenor?
It is important to take Arsenor as prescribed by your doctor. If you miss a dose, it is recommended to take the missed dose as soon as possible. However, it is important not to take more than two doses in one day.
Can Arsenor be used in combination with biologic medications?
Yes, Arsenor can be used in combination with biologic medications such as adalimumab or etanercept, though careful monitoring is recommended.
Does Arsenor increase the risk of infection?
Yes, Arsenor may increase the risk of infection. It is important to discuss any potential risks with your doctor before starting treatment.
What is the most common adverse effect of Arsenor?
The most common adverse effect of Arsenor is nausea.
Is Arsenor approved for the treatment of other skin disorders?
No, Arsenor is not approved for the treatment of other skin disorders. It is only approved for the treatment of plaque psoriasis and psoriatic arthritis.
Does Arsenor cause liver damage?
The use of Arsenor has been associated with an increased risk of liver damage. It is important to discuss any potential risks with your doctor before starting treatment.
Is Arsenor available in other forms besides tablets?
No, Arsenor is only available as an oral tablet.
Can Arsenor be used in combination with systemic medications?
Yes, Arsenor can be used in combination with other systemic medications such as methotrexate or cyclosporine.
Does Arsenor interact with any herbal supplements?
Yes, Arsenor may interact with certain herbal supplements. It is important to discuss any supplements you are taking with your doctor before starting treatment.
Can Arsenor be used in combination with phototherapy?
Yes, Arsenor can be used in combination with phototherapy.
What should I do if I experience any adverse effects while taking Arsenor?
It is important to speak to your doctor if you experience any adverse effects while taking Arsenor. Your doctor may decide to adjust your dose or switch to another treatment.
Does Arsenor cause dizziness?
Yes, Arsenor may cause dizziness. It is important to discuss any potential risks with your doctor before starting treatment.
Does Arsenor cause an increase in blood pressure?
Arsenor has not been shown to be associated with an increase in blood pressure in clinical trials. However, it is important to discuss any changes in blood pressure with your doctor.
Does Arsenor cause gastrointestinal issues?
Yes, Arsenor may cause gastrointestinal issues such as nausea, diarrhoea, and abdominal pain.
Can Arsenor be used with other psoriasis treatments?
Yes, Arsenor can be used in combination with various other psoriasis treatments such as topical medications, systemic medications, and phototherapy.
Can Arsenor be used with topical tacrolimus?
Yes, Arsenor can be used in combination with topical tacrolimus.