Arpizol

Arpizol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Arpizol is a brand name. Its generic name is Aripiprazole.

Introduction

Arpizol is an atypical antipsychotic medication commonly prescribed to treat certain mental health disorders, such as bipolar disorder, schizophrenia, and depression. It works by altering the levels of natural chemicals in the brain, helping to level out moods and reduce psychotic symptoms.

Uses

Arpizol is used to treat the symptoms of schizophrenia, bipolar disorder, and major depressive disorder. It can also be used to treat irritability and mood swings linked to autistic disorder.

Mechanism of Action

Arpizol acts as a partial agonist at various dopamine and serotonin receptors in the brain, helping to alter the levels of these natural chemicals. This can help to normalize mood and reduce psychotic symptoms.

How Long Does it Take to Work?

Arpizol can take up to 6 weeks to reach its full effect in terms of reducing symptoms of mental health disorders. It is important to remain compliant with your dosing schedule and give the medication the necessary time to work.

Absorption

Arpizol is well absorbed orally and has an oral bioavailability of approximately 87%. It is most rapidly absorbed when taken with food.

Route of Elimination

Arpizol is eliminated from the body primarily by the kidneys, with less than 10% of the dose being excreted in the feces.

Dosage

Arpizol dosage can vary depending on the patient's age, medical history, and other medications they may be taking. The following are generally accepted as safe and effective dosage ranges:
  • For adults with schizophrenia or bipolar disorder: the starting dose is usually 10 to 15 mg per day
  • For children and adolescents with schizophrenia or bipolar disorder: the starting dose is usually 2 to 5 mg per day
  • For adults with major depressive disorder: the starting dose is usually 15 mg per day
  • For children and adolescents with major depressive disorder: the starting dose is usually 2.5 mg per day
It is important to talk to your doctor before beginning Arpizol and to follow their dosing direction.

Administration

Arpizol should be taken orally once daily with or without food. It is important to take the medication at the same time every day and to remain compliant with the medication schedule.

Side Effects

Common side effects of Arpizol include weight gain, restlessness, nausea, headache, constipation, dizziness, and dry mouth. Less common side effects include increased blood sugar, muscle pain, difficulty sleeping, and abnormal heart rhythms.

Toxicity

The risk of serious side effects or overdosing with Arpizol is very low. If toxicity is suspected, seek medical attention immediately.

Precaution

Patients taking Arpizol should be monitored regularly for any changes in mental health, as well as any physical changes such as weight gain or changes in blood sugar levels. Patients should also be careful not to operate heavy machinery or drive after taking the medication, as it can cause drowsiness and impair judgment.

Interaction

Arpizol may interact with other medications, herbal supplements, vitamins, or alcohol. It is important to talk to your doctor about all medications and supplements you are taking before beginning Arpizol.

Disease Interaction

Patients with certain medical conditions should not take Arpizol. These conditions include liver or kidney disease, seizure disorders, low blood pressure, and a history of heart attacks. It is important to talk to your doctor about any medical conditions you have before beginning the medication.

Drug Interactions

Arpizol can interact with other medications or drugs and cause unexpected side effects. It is important to tell your doctor about any prescription or over-the-counter medications you are taking before beginning Arpizol.

Food Interactions

Arpizol should be taken with food to maximize absorption and reduce the risk of nausea.

Pregnancy Use

This medication should be avoided during pregnancy unless the potential benefit outweighs the risk to the fetus.

Lactation Use

It is not known if Arpizol is excreted in breast milk. It is important to discuss potential risks with your doctor before taking the medication while breastfeeding.

Acute Overdose

An overdose of Arpizol can be fatal. Contact your doctor or the Poison Control Center immediately if you believe you or someone else may have taken an overdose of Arpizol.

Contraindication

Arpizol is not recommended for use in patients with a seizure disorder, low blood pressure, or any history of heart attack. It should also not be used in conjunction with any other antipsychotic medications.

Use Direction

It is important to take Arpizol as directed by your doctor. Do not adjust dosage without first talking to your doctor. Take the medication with food to reduce the risk of nausea.

Storage Condition

Arpizol should be stored at room temperature, protected from light and moisture, and out of reach of children and pets.

Volume of Distribution

The volume of distribution for Arpizol is approximately 18.3 L/kg.

Half Life

The half life of Arpizol is approximately 75 hours.

Clearance

The clearance of Arpizol is approximately 0.99 L/h/kg.

Here you find in details version of Arpizol

Some Frequently Asked Questions About Arpizol

h2 What is Arpizol? p Arpizol is a medication that works in the brain to treat certain mental/mood disorders (such as bipolar disorder, schizophrenia, Tourette's syndrome, and irritability associated with autism). It is also used in adults to treat major depressive disorder when used in combination with other medications. It may also be used for other conditions as determined by your doctor. h2 What is the mechanism of action of aripiprazole? p Arpizol works by restoring the balance of certain neurotransmitters in the brain, allowing it to work more effectively. It blocks the dopamine D2 receptors, allowing other dopamine receptors to be more effective, as well as activating serotonin 5-HT1A receptors, helping to keep serotonin levels regulated. Arpizol has also been shown to modulate glutamatergic pathways and inhibit serotonin receptors. h2 What are the side effects of Arpizol? p Common side effects of aripiprazole include nausea, vomiting, constipation, headache, dizziness, anxiety, restlessness, drowsiness, shaking, and an inability to stay still. Other more serious side effects that may occur include an increased risk of seizures, suicidal thoughts and behavior, and an increased risk of low blood pressure. If you experience any of these side effects, contact your doctor immediately. h2 How do you take Arpizol? p Arpizol is taken orally in pill form once daily. The dose you are prescribed will depend on your unique condition and may change over time. It is important to always take aripiprazole exactly as prescribed by your doctor. h2 Who should not take Arpizol? p Arpizol is not recommended for people with known hypersensitivity to aripiprazole or to any of the other ingredients in the tablets or injection. It should also not be taken if you are pregnant, trying to become pregnant, or are breastfeeding. Additionally, if you are taking any other prescription or over-the-counter medications, it is important to tell your doctor before you start taking aripiprazole. h2 How long does it take for Arpizol to work? p It generally takes about 1-2 weeks for Arpizol to start working. However, it may take up to 6 weeks for the full therapeutic effect to be seen. During this time, it is important to take the medication exactly as prescribed by your doctor in order to ensure that it is working as expected. h2 Is Arpizol a controlled substance? p Yes, Arpizol is a Schedule II controlled substance in the United States. This means that it is available by prescription only and must be used only as prescribed. It is important to store aripiprazole in a secure location and to only take it as prescribed in order to avoid misuse and addiction. h2 Who manufactures Arpizol? p Arpizol is manufactured by Otsuka Pharmaceutical Co. Ltd., a Japanese pharmaceutical company. It is also manufactured by Teva Pharmaceuticals in the United States. h2 Is Arpizol a psychotropic medication? p Yes, Arpizol is a psychotropic medication. It is classified as an atypical antipsychotic, which means that it works differently from traditional antipsychotic medications. It is used to treat certain mental health conditions including bipolar disorder, schizophrenia, Tourette's syndrome, and irritability associated with autism. h2 How long does Arpizol take to work? p Arpizol generally takes 1-2 weeks to start working, and it may take up to 6 weeks to reach its full therapeutic effect. While taking aripiprazole, it is important to take the medication exactly as prescribed to ensure that it is working as expected. h2 Is Arpizol an antidepressant? p Arpizol is not primarily an antidepressant. It is usually used to treat certain severe mental health conditions such as bipolar disorder, schizophrenia, Tourette's syndrome, and irritability associated with autism. However, it may be used in adults to treat major depressive disorder when used in combination with other medications. h2 What is aripiprazole used for? p Arpizol is used to treat certain mental health conditions including bipolar disorder, schizophrenia, Tourette's syndrome, and irritability associated with autism. It is also used in adults to treat major depressive disorder when used in combination with other medications. h2 Does Arpizol cause weight gain? p Yes, aripiprazole can cause weight gain in some people. It is important to monitor your weight and any changes in your appetite while taking aripiprazole and to speak to your doctor if you notice any sudden or unexplained changes. h2 How does Arpizol work? p Arpizol works by restoring the balance of certain neurotransmitters in the brain, allowing it to work more effectively. It blocks the dopamine D2 receptors, allowing other dopamine receptors to be more effective, as well as activating serotonin 5-HT1A receptors, helping to keep serotonin levels regulated. Arpizol has also been shown to modulate glutamatergic pathways and inhibit serotonin receptors. h2 What is the brand name for Arpizol? p The brand name for Arpizol is Abilify. h2 How long should I take Arpizol? p The length of time that you should take Arpizol will be determined by your treating physician. Generally speaking, it should be taken as prescribed and for the amount of time recommended by your doctor. h2 Are there any interactions between Arpizol and other medications? p Yes, there are certain medications that may interact with aripiprazole. All medications, including herbs and supplements, should be discussed with your doctor. Some medications that may interact with aripiprazole include: anticoagulants, certain medications for depression, seizure medications, certain antibiotics, certain antifungal medications, dexamethasone, and diuretics. h2 Does Arpizol cause insomnia? p Yes, in some people aripiprazole can cause insomnia. This side effect is more common in people who are considered “sensitive” to the medication, so it is important to speak to your doctor if you experience insomnia while taking aripiprazole. h2 Does Arpizol treat anxiety? p Arpizol is not primarily used to treat anxiety, however it may be effective in managing certain psychotic symptoms of anxiety disorders. It is important to speak to your doctor to determine if aripiprazole is the right medication for your particular condition. h2 Does Arpizol cause hair loss? p Hair loss is a possible side effect of aripiprazole, but it is not common. If you experience any sudden hair loss while taking aripiprazole, it is important to speak to your doctor. h2 Is Arpizol safe for long term use? p Yes, according to the research, aripiprazole is generally safe to use for long-term treatment of mental health conditions. However, it is important to talk to your doctor to determine if this is the best medication to treat your particular condition and to discuss any potential side effects or other concerns that you may have. h2 Does Arpizol cause sleepiness? p Yes, Arpizol can cause sleepiness, drowsiness, or a feeling of “slow motion.” This side effect is more common in people who are “sensitive” to the medication. It is important to take any drowsiness or lack of alertness very seriously, and discuss any concerns with your doctor. h2 Does Arpizol cause constipation? p Yes, constipation is a possible side effect of aripiprazole. If you experience constipation while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend dietary or lifestyle changes that can help alleviate the issue. h2 How should Arpizol be stored? p Arpizol should be stored at room temperature, away from moisture and heat, and should be kept out of the reach of children. It is important to store the medication securely to avoid misuse and addiction. h2 Is Arpizol FDA approved? p Yes, Arpizol is approved by the Food and Drug Administration (FDA). It was approved in November 2002 for the treatment of schizophrenia, and in 2007 for the treatment of bipolar disorder. h2 Does Arpizol cause dry mouth? p Yes, dry mouth is a possible side effect of aripiprazole. If you experience dry mouth while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause diarrhea? p Yes, diarrhea is a possible side effect of aripiprazole. If you experience diarrhea while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend dietary or lifestyle changes that can help alleviate the issue. h2 Is Arpizol a narcotic? p No, Arpizol is not a narcotic. It is classified as an atypical antipsychotic and is used to treat certain mental and mood disorders. h2 Does Arpizol cause nausea? p Yes, nausea is a possible side effect of aripiprazole. If you experience nausea while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause dizziness? p Yes, dizziness can be a side effect of aripiprazole. If you experience dizziness while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause headaches? p Yes, headaches are a possible side effect of aripiprazole. If you experience headaches while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause blurred vision? p Yes, blurred vision can be a side effect of aripiprazole. If you experience blurry vision while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause weight loss? p Yes, weight loss is a possible side effect of aripiprazole. If you experience weight loss while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue. h2 Does Arpizol cause memory loss? p Memory loss can be a side effect of aripiprazole, but it is not common. If you experience memory loss while taking aripiprazole, it is important to speak to your doctor. They may be able to recommend a remedy to help alleviate the issue.