Arbitel Plus

Arbitel Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Arbitel Plus is a brand name. Its generic name is Telmisartan + Hydrochlorothiazide.

Introduction

Arbitel Plus is a combination drug containing telmisartan, a selective angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic. It is used to treat hypertension (high blood pressure).

Uses for

Arbitel Plus is prescribed to treat hypertension (high blood pressure) in adults and adolescents (12 years and older). It may in some cases be used to treat heart failure or kidney failure related to hypertension. In addition, it may be used to reduce the risk of stroke or heart attack in patients at risk for these complications.

Mechanism of Action

Telmisartan works by blocking the action of angiotensin II, a hormone which narrows blood vessels and increases blood pressure. Hydrochlorothiazide, a thiazide diuretic, works by increasing the amount of salt and water removed from the body, helping to lower blood pressure.

How long does it take to work?

It can take several weeks of regular use for Arbitel Plus to reach its full effect on blood pressure. However, some people may notice an improvement sooner, typically within 1–2 weeks.

Absorption

Once taken, Arbitel Plus is quickly absorbed in the body, with peak concentration reached within 1-3 hours.

Route of Elimination

After being absorbed in the body, Arbitel Plus is eliminated primarily through the kidneys.

Dosage

The recommended starting dose of Arbitel Plus in adults and adolescents (12 years and older) with hypertension is 40 mg/12.5 mg once daily. Depending on blood pressure response, the dose may be increased to 80 mg once daily, if necessary. The maximum dose is 80 mg/25 mg per day.

Administration

Arbitel Plus should be taken orally with or without food, once daily.

Side Effect

Common side effects of Arbitel Plus includes dizziness, headache, stuffy or runny nose, nausea, abdominal pain, sore throat, cough, fatigue, impotence in men, and menstrual irregularities in women.

Toxicity

Arbitel Plus has been found to be safe when taken as prescribed. On rare occasions, overdose of Arbitel Plus can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Precaution

Arbitel Plus must not be administered during pregnancy, since it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug. The drug should also be used cautiously in patients with liver disease, kidney disease, diabetes, and in elderly patients.

Interaction

Arbitel Plus may interact with other drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Disease Interaction

Arbitel Plus may worsen conditions associated with kidney failure, such as high potassium levels, low blood pressure, and lupus.

Drug Interaction

Drugs that can interact with Arbitel Plus include nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, lithium, ibuprofen, and aspirin.

Food Interactions

No food interactions have been reported with Arbitel Plus.

Pregnancy Use

Arbitel Plus must not be administered during pregnancy, as it can cause harm to the developing fetus. Patients should notify their doctor if they become pregnant while taking the drug.

Lactation Use

It is not known whether Arbitel Plus passes into breast milk. It should be avoided while breastfeeding, as it may cause harm to the nursing infant.

Acute Overdose

Acute overdose of Arbitel Plus can lead to severe hypotension (low blood pressure), orthostatic hypotension (fall in blood pressure when changing posture from sitting to standing), or electrolyte imbalance.

Contraindication

Arbitel Plus should not be used in patients with allergy or hypersensitivity to any of its components, or in patients with severe renal impairment.

Use direction

Arbitel Plus should be taken orally with or without food, once daily.

Storage condition

Arbitel Plus should be stored at room temperature (59–86°F/ 15–30°C).

Volume of Distribution

Arbitel Plus is widely distributed throughout the body, with a volume of distribution of about 4.3 L/kg.

Half Life

The elimination half-life of Arbitel Plus is about 11–14 hours.

Clearance

The total clearance of Arbitel Plus is approximately 0.3 L/hr/kg.

Here you find in details version of Arbitel Plus

Some Frequently Asked Questions About Arbitel Plus

What is Arbitel Plus?

Arbitel Plus is a medication combination containing the drugs telmisartan and hydrochlorothiazide (HCTZ). It is used to lower high blood pressure (hypertension) and treat edema.

How does Arbitel Plus work?

Telmisartan is an angiotensin receptor blocker (ARB) and HCTZ is a thiazide diuretic (water pill). The combination of the two drugs works together to lower blood pressure by blocking the hormone angiotensin II, which normally causes blood vessels to constrict, thus protecting the outer walls of blood vessels and lowering blood pressure.

What are the possible side effects of Arbitel Plus?

Common side effects include headache, dizziness, tiredness, nausea, joint pain, and chest pain. More serious side effects may include electrolyte imbalance and, rarely, allergic reactions or anaphylaxis.

When should I take Arbitel Plus?

Arbitel Plus is usually taken once a day with food. It is important to follow your doctor’s instructions exactly when taking this medication.

Is Arbitel Plus safe?

Yes, Arbitel Plus is generally considered safe when used as prescribed. It is important to tell your doctor about any other medications or health conditions you have before taking Arbitel Plus.

Is Arbitel Plus a diuretic?

Yes, Arbitel Plus contains a diuretic (HCTZ) which helps to remove excess water from the body.

What is the difference between Telmisartan and Hydrochlorothiazide?

Telmisartan is an angiotensin receptor blocker (ARB) and Hydrochlorothiazide (HCTZ) is a thiazide diuretic (water pill). The combination of the two drugs works together to lower blood pressure by blocking the hormone angiotensin II, which normally causes blood vessels to constrict, thus protecting the outer walls of blood vessels and lowering blood pressure.

Can I take Arbitel Plus with other medications?

You should not take Arbitel Plus with other medications without consulting with your doctor. Some medications can interact with Arbitel Plus and cause serious side effects.

What should I do if I forget a dose of Arbitel Plus?

If you forget to take a dose of Arbitel Plus, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and resume your normal dosing schedule. Do not double up on doses.

Does Arbitel Plus cause weight gain?

Arbitel Plus is not known to cause weight gain, although it can cause fluid retention in some people. If you experience unusual weight gain, talk to your doctor.

Can Arbitel Plus be used for other conditions?

Arbitel Plus is primarily used to lower high blood pressure and treat edema. Your doctor may prescribe this medication for other conditions as well.

Is Arbitel Plus covered by insurance?

Yes, Arbitel Plus is generally covered by most insurance plans. Check with your insurance provider for specific details.

Does Arbitel Plus cause drowsiness?

Arbitel Plus may cause drowsiness or dizziness in some people. If you experience any of these side effects, do not drive or operate heavy machinery.

Can I drink alcohol while on Arbitel Plus?

It is not recommended to drink alcohol while taking Arbitel Plus, as alcohol can increase the risk of side effects. If you choose to drink alcohol while taking this medication, do so in moderation and talk to your doctor about any potential interactions.

Can I take Arbitel Plus while pregnant?

Arbitel Plus should not be used by pregnant women, as it can cause harm to the fetus. Talk to your doctor if you are pregnant or planning to become pregnant while taking this medication.

Can I take Arbitel Plus while breastfeeding?

Arbitel Plus should be used with caution in breastfeeding women, as it is not known if it is excreted in breast milk. Talk to your doctor about your individual risks.

What happens if I overdose on Arbitel Plus?

Seek immediate medical attention if you take an overdose of Arbitel Plus. Symptoms of an overdose may include hypotension (low blood pressure), dizziness, and fainting. Do not take more than your prescribed dose.

Does Arbitel Plus affect kidney function?

Arbitel Plus may affect kidney function in some people. This is more likely to occur if you have existing kidney problems. Talk to your doctor about your individual risks.

Does Arbitel Plus cause headaches?

Headache is a common side effect of Arbitel Plus. If the headache becomes severe or persistent, talk to your doctor about other treatment options.

Can Arbitel Plus cause constipation?

Arbitel Plus may cause constipation in some people. If you experience constipation, speak with your doctor about other treatments or diet changes to help relieve your symptoms.

Which drugs interact with Arbitel Plus?

Certain drugs can interact with Arbitel Plus, including potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and lithium. Talk to your doctor about all medications you are taking to minimize drug interactions.

How long does it take for Arbitel Plus to work?

The effect of Arbitel Plus may be noticed within 1- 2 weeks. However, it may take several weeks for the full effects of the medication to be seen. Follow your doctor's instructions relating to how long you should take the medication.

What should I do if I have side effects with Arbitel Plus?

If you experience side effects with Arbitel Plus, such as rash, itching, or difficulty breathing, contact your doctor immediately. You may have an allergic reaction to this medication and will need to stop taking it.

Can Arbitel Plus cause dizziness?

Yes, Arbitel Plus may cause dizziness in some people. If you experience dizziness, do not drive or operate heavy machinery until the dizziness passes.

What should I do if I experience chest pain while taking Arbitel Plus?

If you experience chest pain while taking Arbitel Plus, stop taking the medication and contact your doctor immediately. Chest pain can be a sign of a serious medical condition and should not be ignored.

What is the usual dose of Arbitel Plus?

The usual starting dose of Arbitel Plus is one tablet once a day. Your doctor may increase or decrease your dose as necessary to achieve the desired blood pressure reduction. Do not take more than your prescribed dose.

Can Arbitel Plus be crushed?

Arbitel Plus tablets should not be crushed or split. If you have difficulty swallowing the tablet whole, talk to your doctor or pharmacist for other alternatives.

Can children take Arbitel Plus?

Arbitel Plus is not recommended for children or adolescents under the age of 18. Talk to your doctor about other treatment options for high blood pressure in this age group.

How long should I take Arbitel Plus for?

Arbitel Plus should be taken as instructed by your doctor. Do not stop taking the medication without speaking to your doctor, as this can cause your blood pressure to rise. It is important to follow your doctor's instructions.

Does Arbitel Plus lower cholesterol?

Arbitel Plus may potentially lower cholesterol levels. Talk to your doctor about your cholesterol levels and your risk factors for heart disease and stroke.

Can Arbitel Plus affect my liver function?

Arbitel Plus may cause changes in liver function tests. Talk to your doctor if you experience any symptoms of liver damage, such as nausea, weakness, tiredness, or abdominal pain.

Can Arbitel Plus be taken with food?

Arbitel Plus can be taken with food. Consult your doctor or pharmacist for more information.

Can Arbitel Plus cause elevated blood sugar levels?

Arbitel Plus may cause an increase in blood sugar levels. If you experience signs of hyperglycemia such as increased thirst or urination, contact your doctor for further instruction.

Can Arbitel Plus cause dry mouth?

Yes, Arbitel Plus may cause dry mouth. If this side effect persists or becomes bothersome, talk to your doctor.

Can I take herbal supplements while taking Arbitel Plus?

You should consult your doctor before taking herbal supplements while taking Arbitel Plus. Some supplements may interact with this medication and increase the risk of side effects.

Is Arbitel Plus a generic or brand-name drug?

Arbitel Plus is a brand-name drug. It is not available in a generic form.

Does Arbitel Plus lower blood pressure immediately?

No, Arbitel Plus does not lower blood pressure immediately. It can take 1-2 weeks to see a decrease in blood pressure.

Does Arbitel Plus cause urinary frequency?

Arbitel Plus may cause urinary frequency in some people. If this side effect persists or becomes bothersome, talk to your doctor.

Does Arbitel Plus cause a cough?

Yes, Arbitel Plus may cause a cough in some people. If this side effect persists or becomes bothersome, talk to your doctor.

Does Arbitel Plus help heart failure?

Arbitel Plus may help to reduce the symptoms of heart failure. Talk to your doctor for more information.