Arbit HZ
Arbit HZ Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Arbit HZ is a brand name. Its generic name is Irbesartan + Hydrochlorothiazide.
Introduction
Arbit HZ is a combination drug that is used to treat different conditions including high blood pressure. It is a prescription medication, and it is used to improve the symptoms of hypertension (high blood pressure) in adults.Uses For
Arbit HZ is used to treat high blood pressure. It works by blocking a hormone that causes blood vessels to tighten. It also helps reduce sodium and water retention in the body, which helps lower blood pressure.Mechanism of Action
Arbit HZ works to reduce high blood pressure by blocking angiotensin-converting enzyme (ACE) and by helping the body to excrete more water and less salt. Irbesartan works by blocking the effects of angiotensin II, which is a hormone that causes the blood vessels to contract. Irbesartan blocks the actions of angiotensin II, which helps to relax the blood vessels and reduce blood pressure. Hydrochlorothiazide belongs to a class of drugs called diuretics. It works by making the kidneys excrete more water and salt, which helps to reduce the volume of blood in the body and reduce blood pressure.How long does it take to work?
It usually takes about 1-2 weeks for Arbit HZ to take effect. The full effect of this medicine may take up to 4 weeks.Absorption
Irbesartan is readily absorbed in the gastrointestinal tract with a bioavailability of about 50%. Hydrochlorothiazide is rapidly and completely absorbed in the gastrointestinal tract. However, the extent of absorption is decreased when it is taken with food.Route of Elimination
Irbesartan is eliminated by the kidney through tubular secretion. Hydrochlorothiazide is eliminated by the kidney through glomerular filtration.Dosage
The usual dosage of Arbit HZ is one tablet daily, taken with food. The dose should be tailored to each individual patient.Administration
Arbit HZ should be taken with food or immediately after a meal. It may also be taken with a full glass of water.Side Effects
The most common side effects of Arbit HZ include headache, dizziness, fatigue, nausea, vomiting, dry mouth, and diarrhea.Toxicity
High doses of Arbit HZ may cause an electrolyte imbalance. Symptoms of an electrolyte imbalance include muscle weakness, confusion, seizures, dizziness, and fainting.Precautions
The patient should inform the doctor if he/she has a history of heart disease or kidney disease. The patient should also inform the doctor if he/she is taking any other medications, as some medications may interact with Arbit HZ.Interactions
Arbit HZ may interact with some other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) and Lithium.Disease Interactions
Arbit HZ may interact with some diseases, including diabetes, kidney failure, and liver or heart failure.Drug Interactions
Arbit HZ may interact with some other drugs, including diuretics, ACE inhibitors, beta-blockers, and angiotensin-receptor blockers (ARBs).Food Interactions
Arbit HZ should not be taken with grapefruit, as grapefruit can increase the amount of the medication absorbed by the body, leading to an increased risk of side effects.Pregnancy Use
Arbit HZ is not recommended for use during pregnancy, as the safety of this medication in pregnant women has not been established.Lactation Use
Arbit HZ should not be taken while breastfeeding, as it may pass into the breast milk and may harm the infant.Acute Overdose
Symptoms of an overdose include dizziness, confusion, low blood pressure, weakness, and seizures.Contraindication
Arbit HZ is contraindicated in patients with anuria (lack of urine production) or hypersensitivity to either component.Use Direction
Arbit HZ should be taken as instructed by the doctor. It should be taken at the same time every day, with food.Storage Condition
Arbit HZ should be stored at room temperature, away from light and moisture.Volume of Distribution
The volume of distribution of Arbit HZ is 0.72 L/kg.Half Life
The half-life of Irbesartan is 11-15 hours, and the half-life of Hydrochlorothiazide is 6-15 hours.Clearance
Arbit HZ is cleared from the body by the liver and kidneys.Here you find in details version of Arbit HZ
Some Frequently Asked Questions About Arbit HZ
What is Arbit HZ?
Arbit HZ is a combination drug which contains an Angiotensin receptor blocker (ARB) and diuretic (water pill) that is used to treat high blood pressure.
What is the dosage of Arbit HZ?
The usual recommended starting dose for Arbit HZ is either one tablet containing 150 mg of irbesartan and 12.5 mg of hydrochlorothiazide, or one tablet containing 300 mg of irbesartan and 25 mg of hydrochlorothiazide once a day.
How does Arbit HZ work?
Arbit HZ works by relaxing the blood vessels and reducing the amount of fluid in the body. This helps to lower blood pressure and make it easier for the heart to pump blood around the body.
Who should not take Arbit HZ?
Patients who have known allergies to any of the ingredients in Arbit HZ should not take this medication. Additionally, Arbit HZ could be harmful to pregnant and breastfeeding women, patients with kidney or liver problems, and those who are taking certain medications.
What are the side effects of Arbit HZ?
The most common side effects of Arbit HZ include headache, dizziness, light-headedness, and fatigue. Other side effects may include nausea, vomiting, stomach pain, diarrhea, constipation, muscle pain, or increased urination. In rare cases, Arbit HZ may cause serious side effects such as chest pain, fainting, shortness of breath, yellowing of the skin or eyes, severe allergic reactions, or kidney and liver problems.
What are the precautions for taking Arbit HZ?
Patients should inform their doctor if they are taking any other prescription or over-the-counter medications, as they may interact with Arbit HZ. Patients with kidney or liver problems should use with caution, as Arbit HZ may be dangerous for them. Other precautions include avoiding alcohol, smoking, and over-the-counter cold and allergy medicines while taking this drug.
Where can I buy Arbit HZ?
Arbit HZ is available with a valid doctor’s prescription from most pharmacies. It can also be purchased from online pharmacies with a valid prescription.
How long does it take for Arbit HZ to work?
It usually takes 1-2 weeks for Arbit HZ to reach its full effect. Patients should not stop taking the medication, even if they feel better, until their doctor advises them to do so.
What is the recommended storage condition for Arbit HZ?
Arbit HZ should be stored at room temperature away from direct sunlight and moisture. Do not store in the bathroom or freezer.
What if I miss a dose of Arbit HZ?
If you miss a dose of Arbit HZ, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and take your next dose at the regular time.
Can I take Arbit HZ with other medications?
Arbit HZ may interact with other medications, including diuretics, antifungals, lithium, drugs to treat HIV, and nonsteroidal anti-inflammatory drugs (NSAIDs). Patients should inform their doctor about all medications and health supplements they are taking before starting Arbit HZ.
Can I take Arbit HZ while pregnant?
It is not advised to take Arbit HZ during pregnancy. Pregnant women should talk to their doctor before taking any type of medication.
Can I take Arbit HZ if I have diabetes?
Yes, patients with diabetes can take Arbit HZ. However, it is important to inform your doctor if you have diabetes, as this medication can increase your risk of low blood sugar.
What should I do if I experience side effects while taking Arbit HZ?
If you experience any serious side effects while taking Arbit HZ, you should seek immediate medical attention. If you are experiencing mild side effects, you should talk to your doctor about possible solutions.
Can I take Arbit HZ if I have high cholesterol?
Yes, patients with high cholesterol can take Arbit HZ. However, you should inform your doctor if you have high cholesterol, as this medication may affect your cholesterol levels.
Is Arbit HZ covered by insurance?
The coverage and cost for Arbit HZ may vary depending on individual insurance plans. Patients should contact their insurance provider for more information.
What should I do if I overdose on Arbit HZ?
If you suspect that you have taken an overdose of Arbit HZ, you should seek immediate medical attention. Symptoms of an overdose of this medication may include severe dizziness, fainting, or a rapid or slow heart rate.
What are some common alternatives to Arbit HZ?
Common alternatives to Arbit HZ include other ARB and diuretic combinations such as losartan-HCTZ, valsartan-HCTZ, and olmesartan-HCTZ.
What should I avoid while taking Arbit HZ?
Patients should avoid drinking alcohol while taking Arbit HZ, as it can increase some of the side effects of the medication. Additionally, it is best to avoid activities that require alertness, such as driving, until you know how this medication affects you.
Can I take Arbit HZ if I have a history of heart disease?
Yes, patients with a history of heart disease can take Arbit HZ. However, it is important to talk to your doctor beforehand to make sure it is the right treatment for you.
Which medicines should not be taken together with Arbit HZ?
Certain medications should not be taken together with Arbit HZ, including diuretics, antifungals, lithium, drugs to treat HIV, and nonsteroidal anti-inflammatory drugs (NSAIDs). Talk to your doctor if you are taking any of these medications.
Can I take lemonade or lime juice while taking Arbit HZ?
Yes, patients can take lemonade or lime juice while taking Arbit HZ. However, it is important to note that drinking more than two liters of liquid a day may cause electrolyte imbalances and other health problems.
Can Arbit HZ be used long-term?
Yes, Arbit HZ can be used long-term to treat high blood pressure. It is important to follow your doctor’s instructions and get regular blood pressure checks while taking this medication.
Can I take Arbit HZ while breastfeeding?
It is not recommended to take Arbit HZ while breastfeeding. This medication can pass into breast milk and may cause serious side effects to the baby. Patients should talk to their doctor to determine if this medication is suitable while breastfeeding.
Can Arbit HZ cause weight gain?
Weight gain is a possible side effect of Arbit HZ. Patients should talk to their doctor if they experience any unexplained weight gain while taking this medication.
What foods should I avoid while taking Arbit HZ?
Patients should avoid foods high in sodium while taking Arbit HZ, as this can cause fluid retention. Foods to avoid include potato chips, canned soups, and frozen dinners. Patients should also aim to eat a balanced diet rich in fruits and vegetables.
Can I take Arbit HZ if I have a history of stroke?
Yes, patients with a history of stroke can take Arbit HZ. However, they should inform their doctor beforehand, as this medication may increase the risk of stroke in some patients.
Can I take Arbit HZ if I am over the age of 65?
Yes, patients over the age of 65 can take Arbit HZ. However, they should let their doctor know, as this medication may be more likely to cause side effects in older patients.
Can I use Arbit HZ for long-term blood pressure control?
Yes, Arbit HZ can be used to control high blood pressure long-term. Patients should follow their doctor's instructions and get regular blood pressure checks while taking this medication.
What should I do if I experience an allergic reaction while taking Arbit HZ?
If you experience signs of an allergic reaction while taking Arbit HZ, such as rash, itching, hives, or swelling of the face, lips, or throat, you should seek immediate medical attention.
Can I drink coffee while taking Arbit HZ?
Yes, patients can drink coffee while taking Arbit HZ. However, it is important to avoid drinking more than two or three cups of coffee a day, as this can increase the risk of side effects.
What should I do if I miss a dose of Arbit HZ?
If you miss a dose of Arbit HZ, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and take your next dose at the regular time.
Can I take Arbit HZ if I have an enlarged prostate?
Yes, patients with an enlarged prostate can take Arbit HZ. However, they should inform their doctor about their medical condition, as this medication may worsen the symptoms of an enlarged prostate in some patients.
Can I take Arbit HZ if I have a history of kidney disease?
It is not advised to take Arbit HZ if you have a history of kidney disease. This medication could cause fluid buildup in the body which could be harmful to the kidneys. Patients should talk to their doctor to determine if this medication is suitable.
Can I take Arbit HZ if I am on hemodialysis?
It is not advised to take Arbit HZ if you are on hemodialysis. This medication can cause fluid buildup in the body, which could be dangerous for patients on hemodialysis. Patients should talk to their doctor to determine if this medication is suitable.