Apsol
Apsol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Apsol is a brand name. Its generic name is Amlexanox.
Apsol Introduction
Apsol is an anti-inflammatory drug with potential anti-allergic and anti-asthma activity. It is approved by the Food and Drug Administration (FDA) as an oral drug in both an enteric coating for long-term treatment of allergic rhinitis (seasonal and perennial) and a topical spray for relief of the symptoms of mild to moderate allergic rhinitis.
Uses for Apsol
Apsol is mainly used to treat allergic rhinitis, both seasonal and perennial. It is also used as an adjunct to other therapies for asthma. Apsol has also shown promise in the treatment of certain types of asthma, such as mild intermittent and mild persistent asthma.
Mechanism of action
The exact mechanism of action of Apsol is unknown; however, it is believed to have anti-inflammatory properties. Apsol inhibits the release of histamine and other inflammatory mediators from mast cells and eosinophils. It may also inhibit the binding of leukotrienes to their receptors. As a result, it can reduce mucus secretion and swelling in the nasal passages, and improve airway flow and breathing.
How long does it take to work?
Apsol typically begins to work within 30-60 minutes after administration. The effects of the drug can last for up to 24 hours.
Absorption
When administered in the form of a tablet, Apsol is rapidly and completely absorbed from the gastrointestinal tract. The peak plasma concentration of the drug typically occurs 30 minutes after ingestion.
Route of elimination
Apsol is eliminated mainly through the kidneys, and very little of it is eliminated through the liver.
Dosage
The dosage of Apsol is dependent on the condition being treated and should be adjusted as needed by a medical professional. In general, adults may take between 4 mg and 8 mg, two to four times daily, depending on the severity of the condition. For children, the dose should be reduced to 2 mg two times per day. It is important to follow the instructions of a healthcare provider when taking this medication.
Administration
Apsol can be administered orally by mouth as a tablet, or in the form of a topical spray. When taking the medication orally, it should be swallowed whole with a glass of water. When using the topical spray, spray it into each nostril one time.Side Effects
The most common side effects associated with Apsol include nausea, vomiting, abdominal discomfort, headache, dry mouth, and fatigue. Other possible side effects include dizziness, drowsiness, insomnia, confusion, palpitations, constipation, and tremor.
Toxicity
No cases of overdose with Apsol have been reported. However, if a large amount of the drug is taken, it is advised to seek immediate medical attention.
Precaution
Apsol may interact with certain medications, including other anti-inflammatories, anticholinergics, antibiotics, anticoagulants, or anticonvulsants. Therefore, it is important to inform your healthcare provider of any medications you may be taking. The drug is not recommended for use in individuals with certain medical conditions such as heart failure, liver or kidney disease, or history of allergy to aspirin or other NSAIDs.
Interaction
Apsol may interact with other medications, herbs, or health supplements. Therefore, it is important to tell your healthcare provider about any medications and supplements you may be taking. Also, let your healthcare provider know if you have any allergies or medical conditions that may affect the effectiveness of the medication.
Disease interaction
Apsol may interact with certain medical conditions, such as asthma, heart failure, kidney disease, or history of allergy to aspirin or other NSAIDs. Let your healthcare provider know if you have any of these conditions before using this medication.
Drug interaction
Apsol may interact with other medications, such as anticoagulants, anticonvulsants, antibiotics and other anti-inflammatories. It is important to tell your healthcare provider about all medications you are taking before taking Apsol.
Food interactions
Apsol can interact with certain foods and dietary supplements, such as alcohol and caffeine. Let your healthcare provider know about any dietary supplements and medications you may be taking before taking Apsol.
Pregnancy Use
Apsol is not recommended for use in pregnant women. There is limited data to suggest that the drug may be transferred through breast milk, so its use is not recommended in nursing mothers.
Lactation Use
Apsol is not recommended for use in nursing mothers. There is limited data to suggest that the drug may be transferred through breast milk.
Acute Overdose
No cases of acute overdose with Apsol have been reported; however, if a large amount of the drug is taken, it is advised to seek immediate medical attention.
Contraindication
Apsol is contraindicated in patients with a history of allergy to aspirin or other NSAIDs, and in patients with certain medical conditions such as respiratory failure, heart failure, liver or kidney diseases.
Use Direction
Apsol should be taken as directed by your healthcare provider. Always take the medication with food or after meal. If you are taking the tablet form of the drug, it should be swallowed whole with a glass of water, not crushed, chewed, or dissolved. If you are taking the spray form, spray it into each nostril one time.
Storage Condition
Apsol should be stored at room temperature, away from moisture and heat. Keep the medication away from children and pets.
Volume of Distribution
The volume of distribution of Apsol is not known.
half Life
The half-life of Apsol is 2-3 hours.
Clearance
The clearance of Apsol is not known.
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