Aprocin Eye/Ear Drop

Brand Name: Aprocin
Generic: Ciprofloxacin (Eye/Ear)
Weight: 0.3%
Type: Eye/Ear Drop
Therapeutic Class: Aural Anti-bacterial preparations, Ophthalmic antibacterial drugs
Manufacturer: Aristopharma Ltd.
Price: 70.00
Last Updated: 2020-11-21 18:15:00

Aprocin Eye/Ear Drop Uses

Aprocin Eye/Ear Drop contains Ciprofloxacin (Eye/Ear). Aprocin uses:

Ciprofloxacin (Eye/Ear) Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:

Eye

Corneal Ulcers:

• Pseudomonas aeruginosa

• Serratia marcescens

• Staphylococcus aureus

• Staphylococcus epidermidis

• Streptococcus pneumonia

• Streptococcus (Viridans Group)

Conjunctivitis:

• Haemophilus influenza

• Staphylococcus aureus

• Staphylococcus epidermidis

• Streptococcus pneumoniae

Ear

Otitis externa, acute otitis media, cronic suppurative otitis media. Prophylaxis in otic surgeries such as mastoid surgery.

Aprocin Eye/Ear Drop Doses

Aprocin Eye/Ear Drop contains Ciprofloxacin (Eye/Ear) 0.3%. Aprocin doses:

Eye

Corneal Ulcers: The recommended dosage regimen for the treatment of corneal ulcers is 2 drops into the affected eye every 15 minutes for the first 6 hours and then 2 drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill 2 drops in the affected eye hourly. On the third through the fourteenth day, place 2 drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

Conjunctivitis: The recommended dosage regimen for the treatment of bacterial conjunctivitis is 1 or 2 drops instilled into the conjunctival sac(s) every 2 hours while awake for 2 days and one or 2 drops every 4 hours while awake for the next 5 days.

 

Ear

For all infections, 2-3 drops every 2-3 hours initially, reducing the frequency of the instillation with control of infection. Treatment should be continued at least 7 days.

 

Side Effects

The most frequently reported drug related adverse reaction is local burning or discomfort. In corneal ulcer studies with frequent administration of the drug, white crystalline precipitates were seen in approximately 17% of patients. Other reactions occurring in less than 10% of patients included lid margin crusting, crystals/scales, foreign body sensation, itching, conjunctival hyperemia and a bad taste following instillation. Additional events occurring in less than 1% of patients included corneal staining, keratopathy/keratitis, allergic reactions, lid edema, tearing, photophobia, corneal infiltrates, nausea and decreased vision.

Introduction

Ciprofloxacin (Eye/Ear) drops (Ciprofloxacin Hydrochloride ophthalmic solution) is a synthetic, sterile, multiple dose, antimicrobial for topical use. Ciprofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of gram positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- 3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its empirical formula is C17H18FN3O3.HCl.H2O.

Aprocin Precaution

As with other antibacterial preparations, prolonged use of ciprofloxacin may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated.

Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.

Interaction

Specific drug interaction studies have not been observed with ophthalmic Ciprofloxacin.

Pregnancy Lactation use

Pregnancy Category C. There are no adequate and well controlled studies in pregnant women. Ciprofloxacin (Eye/Ear) Solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

It is not known whether topically applied ciprofloxacin is excreted in human milk. Caution should be exercised when Ciprofloxacin (Eye/Ear) Solution is administered to a nursing mother.

Contraindication

Hypersensitivity to quinolone group of antibacterials or any of the components of the formulation.

Special Warning

Pediatric use: Safety and effectiveness in children under 1 year of age have not been established.

Acute Overdose

A topical overdose may be flushed from the eye/s with warm tap water.

Interaction with other Medicine

Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin.

Storage Condition

Store below 30° C in a cool and dry place protected from light. Keep out of reach of children. Do not touch the dropper tip to surfaces since this may contaminate the solution. Do not use after 30 days of first opening.

Aprocin Eye/Ear Drop price in Bangladesh 70.00