|Therapeutic Class:||Tetracycline Group of drugs|
|Manufacturer:||Apex Pharmaceuticals Ltd.|
|Last Updated:||2020-11-21 18:15:00|
Apdox Capsule contains Doxycycline. Apdox uses:
Apdox Capsule has a very wide spectrum of activities and has been used in the treatment of a large number of infections caused by susceptible organisms.
Respiratory tract infections: Pneumonia, influenza, pharyngitis, tonsillitis, bronchitis, sinusitis, otitis media and other streptococcal and staphylococcal infections where tetracycline resistance is not a problem.
Genitourinary tract infections: Pyelonephritis, cystitis, urethritis, gonorrhea, epididymitis, syphilis, chancroid and granuloma inguinale.
Chlamydia: Lymphogranuloma venereum, psittacosis, trachoma.
Intestinal diseases: Whipples disease, tropical sprue, blind loop syndrome.
In acute intestinal amoebiasis: Apdox Capsule may be a useful adjunct to amoebicides.
Bacillary infections: Brucellosis, tularemia, cholera, travelers diarrhea
Acne: Acne vulgaris, acne conglobata and other forms of acne.
Other infections: Actinomycosis, yaws, relapsing fever, leptospirosis, typhus, rickettsial pox and Q fever, Cellulitis furunculosis, abscess and infections caused by Mycobacterium marinum, Bordetella pertussis and Bacillus anthracis.
Apdox Capsule contains Doxycycline 100 mg. Apdox doses:
Relapsing fever and louse-borne typhus:
Prophylaxis of scrub typhus:
Chloroquine resistant falciparum malaria acute attack:
Treatment and postexposure prophylaxis of inhalation anthrax:
Prophylaxis of chloroquine-resistant malaria:
Susceptible infections: 200 mg on day 1 followed by 100-200 mg daily depending on the severity of infection.
Gastrointestinal disterbances,eg. anorexia, vomiting, dysentry etc. overgrowth of resistant organisms may cause Glossitis, Stomatitis, or Staphylococcal enterocolitis; Apart from these skin rashes, purpura may occur. Photosensitivity and dermatological reactions are rare.
Apdox Capsule inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It has bacteriostatic activity against a broad range of gm+ve and gm-ve bacteria.
During development of teeth (last trimester of pregnency, upto 12 yrs of age) the use of tetracyclines may lead to discoloration of teeth. So tetracyclines should not be administered during these periods
Should not be taken with antacids, milk, other alkalis e.g. calcium, magnesium and iron, penicillin, anticoagulants, anti-diabetic agents, anticonvulsants and enzyme inducing drugs.
Pregnancy: Apdox Capsule should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the fetus.
Lactation: Apdox Capsules enter breast milk, and mothers taking these drugs should not breastfeed their child.
Hypersensitivity to doxycycline and any of the tetracyclines. Concurrent use with methoxyflurane. Lactation
Neonates and children: Apdox Capsule may cause permanent discoloration of the teeth and so is contraindicated for neonates and children under 12 years.
Elderly: No special precautions are necessary in the elderly.
It should be stored in a dry place at room temperature.
Apdox Capsule price in Bangladesh 1.75