Ansulin

Ansulin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ansulin is a brand name. Its generic name is Insulin human + Isophane Insulin Human.

Introduction

Insulin Human + Isophane Insulin Human is a combination of regular human insulin and a slow-acting insulin analog called isophane insulin human (NPH). It is used to increase insulin levels in people with diabetes. It is available in a vial or a pre-filled pen and must be injected under the skin.

Uses For

Insulin Human + Isophane Insulin Human is used to improve glucose control in adults and children with diabetes mellitus. It helps to reduce the risk of long-term complications caused by high blood sugar levels.

Mechanism of action

Insulin is a hormone produced in the pancreas by beta cells. It facilitates the movement of glucose from the bloodstream into cells, where it is used to produce energy. Insulin Human + Isophane Insulin Human works by increasing the amount of insulin in the body and helping to bring down blood sugar levels.

How Long Does It Take to Work?

Regular human insulin starts working within 15-30 minutes and lasts for up to 8 hours. Isophane insulin human (NPH) takes effect in 1-2 hours and lasts for up to 24 hours. When taken together, Insulin Human + Isophane Insulin Human begins to work within 30 minutes and lasts up to 24 hours.

Absorption

Insulin Human + Isophane Insulin Human is rapidly and completely absorbed when injected into subcutaneous tissues. The rate and extent of absorption depend on the injection site and concentration of the insulin.

Route of elimination

Insulin is metabolized by the liver and kidneys and then eliminated by the bladder as urine.

Dosage

The recommended dosage of Insulin Human + Isophane Insulin Human may vary depending on weight, age, gender, medical condition, and other medications taken. It is important to follow the instructions given by the doctor or pharmacist. Generally, the initial dosage is 3 units in the morning and 3 units in the evening. The dose may be increased or decreased as necessary. It is always recommended to consult a doctor or healthcare provider before taking any medication.

Administration

Insulin Human + Isophane Insulin Human is injected subcutaneously (under the skin) in the arms, abdomen, thighs, and buttocks. The injection should be done in the same spot each time to reduce any potential skin irritation.

Side effects

Common side effects of Insulin Human + Isophane Insulin Human include hypoglycemia (low blood sugar levels), weight gain, dizziness, headaches, and nausea. Rare side effects include rapid breathing, chest pain, swollen ankles, and blurred vision.

Toxicity

Insulin Human + Isophane Insulin Human has an extremely low toxicity profile and is considered safe when taken as directed.

Precaution

Insulin Human + Isophane Insulin Human should be taken with caution in people with allergies, diabetes, thyroid disease, kidney or liver disease, heart failure, and in pregnant and lactating women.

Interactions

Insulin Human + Isophane Insulin Human may interact with certain medications, such as blood pressure drugs, steroids, diabetes medications, and certain barbiturates. It may also interact with certain foods, drinks, and herbs. It is important to inform your doctor and pharmacist about all medications and supplements that you are taking.

Drug Disease Interactions

Insulin Human + Isophane Insulin Human may interact with certain diseases, such as kidney and liver disease, thyroid disease, congestive heart failure, and allergies. It is important to inform your doctor and pharmacist about your medical conditions before taking this medication.

Drug-Food Interactions

Insulin Human + Isophane Insulin Human may interact with certain foods, drinks, and herbs. Alcohol, caffeine, sugar, and high-fat foods should be avoided when taking this medication.

Pregnancy Use

Insulin Human + Isophane Insulin Human should be used with caution in pregnant women. In general, it is recommended that pregnant women only use this medication when absolutely necessary.

Lactation Use

Insulin Human + Isophane Insulin Human should be used with caution in breastfeeding women. Generally, it is recommended that breastfeeding women only use this medication when absolutely necessary.

Acute Overdose

An overdose of Insulin Human + Isophane Insulin Human can be serious and requires immediate medical attention. Symptoms of an overdose may include nausea, vomiting, feeling dizzy, drowsiness, confusion, and cold sweats.

Contraindication

Insulin Human + Isophane Insulin Human is contraindicated in people with hypersensitivity to any of its components and in people with diabetic ketoacidosis.

Use Direction

Insulin Human + Isophane Insulin Human should be used exactly as prescribed by the doctor. The medication should be injected subcutaneously (under the skin) as directed. It is important to follow the instructions in the patient information leaflet carefully.

Storage Condition

Insulin Human + Isophane Insulin Human should be stored at room temperature (less than 30°C) and protected from light. It should not be frozen or placed in direct sunlight. The vial or pre-filled pen should be used within 28 days after opening.

Volume of Distribution

Insulin Human + Isophane Insulin Human has a volume of distribution of 1-1.5 L/kg. This means that it distributes mainly in the tissues and not in the bloodstream.

Half Life

The half-life of Insulin Human + Isophane Insulin Human is 4-8 hours. This means that it starts to be eliminated from the body after 4-8 hours.

Clearance

Insulin Human + Isophane Insulin Human has a clearance rate of 5–7 mL/min/kg. This means that it is cleared from the body at a steady rate of 5–7 mL/min/kg.

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