Anacaine HC Cream

Brand Name: Anacaine HC
Generic: Hydrocortisone + Lidocaine
Weight: (5 mg+30 mg)/gm
Type: Cream
Therapeutic Class: Drugs used in Ano-rectal region
Manufacturer: Incepta Pharmaceuticals Limited
Price: 140.00
Last Updated: 2020-11-20 18:15:00

Anacaine HC Cream Uses

Anacaine HC Cream contains Hydrocortisone + Lidocaine. Anacaine HC uses:

Hydrocortisone plus Lidocaine cream is used for the anti-inflammatory and anesthetic relief of itching, pain, soreness and discomfort due to hemorrhoids, anal fissures, pruritus ani and similar conditions of the anal area.

Anacaine HC Cream Doses

Anacaine HC Cream contains Hydrocortisone + Lidocaine (5 mg+30 mg)/gm. Anacaine HC doses:

Apply twice daily around the anal opening in a thin layer using an applicator.

 

Side Effects

Side effects like Rectal bleeding, Swelling of the skin, Adrenal suppression, Anaphylaxis, Angioedema, Cushing syndrome, Hirsutism, Acne, Cutaneous and subcutaneous atrophy, Dry scaly skin, Urticaria.

Introduction

Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Lidocaine is an amide type local anesthesia. It stabilises the neuronal membrane and inhibits Na ion movements, which are necessary for conduction of impulses. In the heart, lidocaine reduces depolarisation of the ventricles during diastole and automaticity in the His-Purkinje system. Duration of action potential and effective refractory period are also reduced.

Anacaine HC Precaution

If extensive areas are treated, the possibility of systemic absorption exists. Systemic absorption of topical steroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glycosuria in some patients. If irritation or sensitivity occurs or infection appears, discontinue use and institute appropriate therapy.

Interaction

This cream should be used with caution together with dental injection anaesthesia, other local anaesthetics or agents structurally related to local anaesthetics of amide type eg, antiarrhythmic drugs (eg, mexiletine), as the toxic effects of these drugs are additive.

Patients treated with class III antiarrhythmic drugs (eg, amiodarone) should be closely observed and ECG monitoring should be considered, as the cardiac effects of lidocaine and class III antiarrhythmic drugs can be additive.

Drugs that inhibit the metabolism of lidocaine (eg, cimetidine or ?-blockers) may cause potentially toxic plasma concentrations when lidocaine is given in repeated high doses over a long time period. Such interactions are of no clinical importance following short-term treatment with lidocaine at recommended doses.

Pregnancy Lactation use

Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Lactation: Unknown if distributed in breast milk; exercise caution

Contraindication

Patients with a history of hypersensitivity to any of its ingredients.

Special Warning

 

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

 

Anacaine HC Cream price in Bangladesh 140.00

Related Drugs

None found