|Therapeutic Class:||Anti vertigo drugs, Anti-emetic drugs|
|Last Updated:||2020-11-20 18:15:00|
Ametil Tablet contains Prochlorperazine. Ametil uses:
Ametil Tablet Maleate Tablet: Each tablet contains Ametil Tablet maleate 5 mg.
Ametil Tablet Mesilate Syrup: Each 5 ml syrup contains Ametil Tablet maleate 5 mg
Ametil Tablet Mesilate Injection: Each 1 ml ampoule contains Ametil Tablet mesilate 12.5 mg.
Ametil Tablet contains Prochlorperazine 5 mg. Ametil doses:
Children (not recommended in children <10 kg or <2 years):
Adults: 5-10 mg 3-4 times/day; usual maximum:40 mg/day
Drowsiness, jaw, neck, and back muscle spasms, fine worm-like tongue movements, rhythmic face, mouth, or jaw movements, slow or difficult speech, difficulty swallowing, restlessness and pacing, tremors, shuffling walk, skin rash, yellowing of the skin or eyes.
Ametil Tablet is a potent phenothiazine antipsychotic, derivative of the piperazine group, now largely used as an antiemetic and to treat vertigo. The effects of this drug is apparent at all levels of the nervous system. It antagonizes postsynaptic dopamine D1 receptor that activates adenylate cyclase and synthesis of cAMP. It also antagonizes D2 receptors which do not activate adenylate cyclase. It also inhinits pre- and post synaptic adrenoreceptors and also acetylcholine, serotonin and histamine receptors. These various pharacodynamic actions combine to produce not only antipsychotic, but also central antiemetic and sedative effects.
Caution should be taken while performing tasks that require alertness, such as driving or using machinery. Use of alcohol can cause extreme drowsiness. This medication may increase sensitivity to sunlight. Prolonged sun exposure should be avoided and a sunscreen and protective clothing should be taken when anybody is exposed to the sun. This medication can reduce sweating making more susceptible to heat stroke.
Alcohol, barbiturate & other sedatives may increase the CNS depressant action. Some drugs like Antacids, antiparkinson's drug, lithium may interfere the absorption of Ametil Tablet. This drug may interfere the plasma concentration of Propanolol, Phenobarbital.
No evidence of adverse effects of this drug has been reported during pregnancy & lactation.
Hypersensitivity to prochlorperazine or any component of the formulation, severe CNS depression; coma; should not be used in children <2 years of age or <10 kg.
Symptoms of overdose include deep sleep, coma, extrapyramidal symptoms, abnormal involuntary muscle movements, and hypotension.
Store in a cool and dry place, protected from light and moisture.
Ametil Tablet price in Bangladesh 0.64