Alphagen Eye Drop

Brand Name: Alphagen
Generic: Brimonidine Tartrate
Weight: 0.2%
Type: Eye Drop
Therapeutic Class: Drugs for miotics and glaucoma
Manufacturer: Eskayef Bangladesh Ltd.
Price: 112.00
Last Updated: 2020-11-21 18:15:00

Alphagen Eye Drop Uses

Alphagen Eye Drop contains Brimonidine Tartrate. Alphagen uses:

It is effective for lowering intraocular pressure in patients with chronic open-angle glaucoma or ocular hypertension.

Alphagen Eye Drop Doses

Alphagen Eye Drop contains Brimonidine Tartrate 0.2%. Alphagen doses:

The recommended dose is 1 drop of ophthalmic solution in the affected eye(s) twice daily (doses taken approximately 12 hours apart).

If more than one topical ophthalmic medicine is to be used, other eye drops should not be used within 5 to 10 minutes of using this eye drops.

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.

 

Side Effects

Headache; itching of eye; redness of eye or inner lining of eyelid; swelling of eyelid; tearing of eye.

Introduction

Brimodin contains the active ingredient brimonidine. It is a relatively selective alpha-2 adrenergic receptor agonist and approximately 1000 times more selective for the alpha-2 adrenoceptor than the alpha-1 adrenoceptor.

Topical administration of brimonidine decreases intraocular pressure (IOP) in humans. When used as directed, brimonidine ophthalmic solution reduces elevated IOP with minimal effect on cardiovascular parameters.

Brimonidine has a rapid onset of action, with the peak ocular hypotensive effect occurring at approximately 2 hours post-dosing. The duration of effect is 12 hours or greater.

Fluorophotometric studies in animals and humans suggest that brimonidine has a dual mechanism of action. Brimonidine lowers IOP by reducing aqueous humor production and increasing uveoscleral outflow.

Alphagen Precaution

General

Brimonidine ophthalmic solution 0.2% should be used with caution in patients with known hypersensitivity to other alpha-adrenoceptor agonists.

Although brimonidine had minimal effect on blood pressure and heart rate of patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease.

Brimonidine has not been studied in patients with hepatic or renal impairment; caution should be exercised in treating such patients.

Brimonidine should be used with caution in patients with depression, cerebral or coronary insufficiency.

Interaction

Although specific drug interaction studies have not been conducted with brimonidine, the possibility of an additive or potentiating effect with CNS depressants (alcohol, barbiturates, opiates, sedatives, or anesthetics) should be considered.

Pregnancy Lactation use

Pregnancy:

Brimonidine has not been studied in pregnant women. Studies in animals have shown that brimonidine crosses the placenta, but very high doses have not been shown to cause harmful effects in the fetus.

Lactation:

It is not known whether brimonidine passes into human breast milk. However, it has been shown to pass into the milk of nursing animals.

Contraindication

This eye drops are contraindicated in patients with hypersensitivity to brimonidine tartrate or any component of this medication.This product is also contraindicated in patients receiving monoaminase oxidase inhibitor therapy.

Special Warning

 

Acute Overdose

No data is available on overdosage of brimonidine ophthalmic solution in humans.

Interaction with other Medicine

 

Storage Condition

Store in a cool, dry place & protected from light.

Keep out of reach of children.

Do not use more than 4 weeks after opening.

Alphagen Eye Drop price in Bangladesh 112.00