Allynol

Allynol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Allynol is a brand name. Its generic name is Allylestrenol.

Introduction

Allynol (INN) is a synthetic steroidal progestin with antigonadotropic and antiglucocorticoid activity used as a treatment for recurrent miscarriage and threatened miscarriage.

Uses for

Allynol is indicated for the prevention and treatment of recurrent and threatened miscarriages, and for the prevention of preterm labor.

Mechanism of Action

Allynol is believed to act mainly through its estrogenic component. It promotes the development of the endometrium, enhancing the likelihood of successful implantation of a fertilized ovum. It also improves the strength of uterine contractions and exerts a sedative effect on the uterus and relaxes its smooth muscles.

How Long Does It Take to Work?

Allynol begins to work immediately on administration, although its effects may not be fully manifest in the body until some weeks later. For example, if it is being used to reduce the risk of preterm labor, its effects may be seen within the week following administration.

Absorption

Allynol is rapidly and completely absorbed from the gastrointestinal tract following oral administration.

Route of Elimination

Allynol is metabolized primarily in the liver and excreted in the bile as metabolites. Approximately 40% of a dose of allylestrenol is excreted in the urine and 10% in the feces.

Dosage

The recommended starting dose of allylestrenol is 10 mg three times daily for three to six days. The dose may be increased up to 20 mg three times daily depending on the patient's response to treatment.

Administration

Allynol is taken orally, usually with a full glass of water, after meals or at bedtime.

Side Effect

The most frequently reported side effects of allylestrenol include nausea, dizziness, bloating, and breast tenderness.

Toxicity

No cases of toxicity from allylestrenol have been reported.

Precautions

Allynol should be used with caution in patients who have a history of liver or kidney disease, diabetes, or any other endocrine disorder. Women taking allylestrenol should not breastfeed while using the drug.

Interactions

Allynol may interact with certain medications and reduce their effectiveness. Patients taking hormone replacement therapy, oral contraceptives, or anticoagulants should not take allylestrenol.

Disease Interactions

Allynol should not be used in patients with a history of any of the following conditions: stroke, breast cancer, endometrial hyperplasia, or a history of jaundice or liver disease.

Drug Interactions

Allynol may interact with certain medications and reduce their effectiveness. Patients taking hormone replacement therapy, oral contraceptives, or anticoagulants should not take allylestrenol. This drug should also not be used in combination with barbiturates, phenytoin, cyclosporine, or any other drug metabolized by CYP3A4 enzyme.

Food Interactions

It is not known if allylestrenol interacts with food. Patients should discuss diet and potential food interactions with their doctor prior to beginning treatment.

Pregnancy Use

Allynol should not be used during pregnancy as it may cause harm to the fetus.

Lactation Use

It is not known if allylestrenol is excreted in breast milk. This drug should not be used while breastfeeding.

Acute Overdose

No cases of acute overdose of allylestrenol have been reported. However, if an overdose is suspected, contact a healthcare provider immediately.

Contraindication

Allynol should not be used in patients with any of the following conditions: porphyria, thromboembolism, undiagnosed vaginal bleeding, or a history of breast or endometrial cancer.

Use Direction

Allynol should be taken orally, usually with a full glass of water, after meals or at bedtime. The recommended starting dose is 10 mg three times daily for three to six days. The dose may be increased up to 20 mg three times daily depending on the patient's response to treatment.

Storage Condition

Allynol should be stored at room temperature in a tight, light-resistant container. It should not be stored in the bathroom or near any heat source.

Volume of Distribution

The volume of distribution of allylestrenol is approximately 18 – 22 L/kg.

Half Life

The half-life of allylestrenol is estimated to range from 3.4 – 7.5 hours.

Clearance

The average clearance of allylestrenol is approximately 5.1 mL/min/kg.

Here you find in details version of Allynol

Some Frequently Asked Questions About Allynol

What is Allynol?

Allynol is a synthetic progestogen, or a man-made hormone, used in the treatment of threatened abortion and habitual abortion.

What is Allynol used for?

Allynol is used to prevent threatened miscarriage and habitual abortion in pregnant women. It is also used in combination with estrogen to treat secondary amenorrhea.

What is the dosage of Allynol?

The usual dose of Allynol is 5 mg to 10 mg a day. Dosage adjustments may be required depending on the individual patient’s condition.

What are the side effects of Allynol?

The most common side effects of Allynol include nausea, vomiting, abdominal pain, headaches, drowsiness, and diarrhea. Other serious side effects may include depression, skin rash, and facial swelling. If any of these side effects occur, seek medical attention right away.

Can Allynol be used in combination with other medications?

Allynol may interact with certain medications, so it should not be used in combination with other medications without consulting a doctor. Always make sure to tell your doctor about all medications that you are taking.

What precautions should be taken while consuming Allynol?

Never take more than the prescribed dose of Allynol. Also, if you are pregnant or planning to become pregnant, consult your doctor before using Allynol. Be sure to tell your doctor if you are breastfeeding.

What are the contraindications for Allynol?

Allynol should not be used in people who are hypersensitive to this drug or any of its components. It should also not be used in people with a history of stroke or thromboembolic disease.

Is Allynol available in generic form?

Yes, Allynol is available in generic form.

What is the price of Allynol?

The price of Allynol varies depending on the pharmacy and where it is purchased. It is typically less expensive in generic form.

Is Allynol available over the counter?

No, Allynol is a prescription medication and is not available over the counter.

What is the mechanism of action of Allynol?

Allynol works by stopping the release of certain hormones that are responsible for triggering miscarriage and habitual abortion. It also helps to reduce the risk of premature delivery.

How long does it take for Allynol to work?

The effects of Allynol typically begin to be felt within one to two weeks of starting treatment. It is important to continue taking Allynol as prescribed in order for it to be effective.

Can Allynol be taken during pregnancy?

Yes, Allynol can be used in pregnant women in order to prevent miscarriage and habitual abortion. However, it should not be used in the last three months of pregnancy without consulting a doctor.

Are there any known drug interactions with Allynol?

Yes, Allynol may interact with certain drugs, so it is important to tell your doctor about any medications or supplements you are taking before taking Allynol.

Can Allynol be taken with anticoagulant drugs?

No, Allynol should not be taken with anticoagulant drugs without consulting a doctor first.

Can Allynol be used in patients with liver or kidney diseases?

Yes, Allynol may be used in patients with liver or kidney diseases, but the dose may need to be adjusted for these patients. Consult a doctor for more information.

Are there any foods that should be avoided with Allynol?

There are no foods that should be avoided while taking Allynol, however it is important to follow a healthy, balanced diet to ensure optimal health.

Can Allynol cause weight gain?

Weight gain is not a common side effect of Allynol, although some patients may experience an increase or decrease in appetite.

Does Allynol affect fertility?

Allynol has not been shown to affect fertility. However, it is important to consult a doctor if you are planning to become pregnant while taking Allynol.

Can Allynol cause sleep disturbances?

Yes, Allynol can cause sleep disturbances, such as insomnia or vivid dreams. If this occurs, then consulting a doctor is recommended.

Can Allynol cause mood changes?

Yes, Allynol can cause mood changes, such as increased anxiety or depression. If this occurs, then consult a doctor.

Can Allynol affect menstrual cycles?

Yes, Allynol can affect menstrual cycles. This is because it prevents the body from releasing hormones that are responsible for triggering ovulation. It can also lead to irregular bleeding.

Can Allynol cause headaches?

Yes, Allynol can cause headaches in some patients. If you experience a persistent or severe headache while taking Allynol, then consult a doctor.

Can Allynol lower blood pressure?

Yes, Allynol can lower blood pressure in some patients. It is important to monitor your blood pressure regularly while taking Allynol.

Can Allynol be used to treat breast cancer?

No, Allynol should not be used to treat breast cancer. It is important to consult a doctor before taking any medication for breast cancer.

Is Allynol linked to an increased risk of cancer?

No, Allynol is not linked to an increased risk of cancer. However, it is important to consult a doctor if you are concerned about the potential risk of cancer while taking Allynol.

Does Allynol affect the liver?

Yes, Allynol can affect the liver in some patients. It is important to monitor your liver functions regularly while taking Allynol.

Can Allynol be used in women of childbearing age?

Yes, Allynol can be used in women of childbearing age, but it should not be used for the treatment of pregnancy unless specifically prescribed by a doctor.

Can Allynol cause skin rashes?

Yes, Allynol can cause skin rashes in some patients. If you experience any skin rashes while taking Allynol, then consult a doctor for treatment.

Can Allynol affect libido?

Yes, Allynol can have an effect on libido in some patients. Consult a doctor if you are experiencing any changes in your libido while taking Allynol.

Does Allynol affect the heart?

Yes, Allynol can affect the heart in some people. It is important to inform your doctor if you have any heart-related conditions before taking Allynol.

Does Allynol accumulate in the body?

No, Allynol is not known to accumulate in the body. This means that it is not necessary to adjust the dosage of Allynol based on the amount of time it has been taken.

Is Allynol an anti-inflammatory drug?

No, Allynol is not an anti-inflammatory drug. It is a synthetic progestogen used for the prevention of miscarriage and habitual abortion.

Can Allynol be used to induce labor?

No, Allynol should not be used to induce labor unless specifically prescribed by a doctor.

Can Allynol cause drowsiness?

Yes, Allynol can cause drowsiness in some patients. It is important to be aware of how Allynol affects you before operating any machinery or driving a vehicle.

Does Allynol cause hair loss?

No, Allynol does not cause hair loss. However, it is important to consult a doctor if you experience any unusual hair loss while taking Allynol.

Can Allynol cause breast tenderness?

Yes, Allynol can cause breast tenderness in some patients. If this occurs, then consult a doctor.

Can Allynol be taken while breastfeeding?

Yes, Allynol can be taken while breastfeeding, but it is important to inform your doctor if you are breastfeeding while taking Allynol.

Can Allynol cause visual disturbances?

Yes, Allynol can cause visual disturbances, such as blurred vision or double vision. If this occurs, then consult a doctor.

Does Allynol cause nausea?

Yes, Allynol can cause nausea in some patients. If you experience persistent or severe nausea while taking Allynol, then consult a doctor.