Albutein Injection

Brand Name:	Albutein
Generic:	Albumin (Human)
Weight:	5%
Type:	Injection
Therapeutic Class:	Plasma expanders
Manufacturer:	Grifols Biologicals Inc, USA
Price:	5.60
Last Updated:	2020-11-21 18:15:00

Albutein Injection Uses

Albutein Injection contains Albumin (Human). Albutein uses:

Burns, Hypovolemia, Hypoalbuminemia, Hypoproteinaemia, Adult Respiratory Distress Syndrome, Nephrosis, Cardiopulmonary Bypass Surgery, Hemolytic Disease of the Newborn, Ovarian Hyperstimulation Syndrome, Acute hypovolaemic shock, Neonatal hyperbilirubinaemia

Albutein Injection Doses

Albutein Injection contains Albumin (Human) 5%. Albutein doses:

25% solution:

• Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: 1 -2 ml/minute.
• Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: 1 -2 ml/minute. Not to exceed 250 g/48 hr or 6 g/kg/day

20% solution:

• Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 1 -2 ml/minute
• Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 1 -2 ml/minute
• Intravenous Hypoproteinaemia for adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 1 -2 ml/minute
• Intravenous Neonatal hyperbilirubinaemia for child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 1 -2 ml/minute
• Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 1 -2 ml/min

5% solution:

• Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute.
• Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute.
• Intravenous Hypoproteinaemia for adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 5 ml/minute.
• Intravenous Neonatal hyperbilirubinaemia for child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 5 ml/minute.
• Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 5 ml/min.

 

Side Effects

Allergic reactions, nausea, vomiting, increased salivation, fever and chills; vascular overload, haemodilution and pulmonary oedema.

Introduction

Human albumin increases intravascular oncotic pressure and causes movement of fluids from interstitial into intravascular space. Human albumin solutions are available in various concentrations. Solutions containing 5% human albumin are usually used in hypovolemic patients, whereas more concentrated 25% solutions are recommended in patients in whom fluid and sodium intake must be minimised e.g. patients with hypoproteinaemia or cerebral oedema or in paediatric patients.

Albutein Precaution

Hypertension or low cardiac reserve; additional fluids for dehydrated patients. Monitor for signs of cardiac overload in injured or postoperative patients. May carry risk of viral transmission. Volume admin and rate of infusion must always be individualised according to situation and response.

Interaction

 

Pregnancy Lactation use

Pregnancy Category C. Animal reproduction studies have not been performed with Albutein Injection. It is also not known whether Albutein Injection can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Albutein Injection should be given to a pregnant woman only if necessary.

Labor and Delivery: It is also not known whether Albutein Injection can cause fetal harm when administered to a woman during labor or delivery of if it will affect reproductive capacity. Albutein Injection should be given during labor or delivery only if necessary.

Nursing Mothers: It is not known whether this drug is excreted in human milk. Albutein Injection should be given to nursing mothers only if necessary. Because many drugs are excreted in human milk, caution should be exercised when Albutein Injection is administered to a lactating woman.

Contraindication

Cardiac failure, severe anaemia, history of hypersensitivity, parenteral nutrition.

Special Warning

Pediatric Use: Data on the use of Albutein Injection 20% in children including premature babies are very limited. The product should be administered to pediatric patients only if needed.

Geriatric Use: Clinical studies did not include a sufficient number of subjects aged 65 and older to determine whether they respond differently from younger subjects.

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

• Albutein Injection may be stored for 36 months at 2 to 25° C from the date of manufacture.
• Store protected from light.
• Do not freeze.
• Do not use after expiration date.
• Do not use if turbid.

Albutein Injection price in Bangladesh 5.60