|Weight:||50 mg/5 ml|
|Therapeutic Class:||Drugs for cutaneous mycoses, Drugs for subcutaneous and systemic mycoses|
|Manufacturer:||Ambee Pharmaceuticals Ltd.|
|Last Updated:||2020-11-22 18:15:00|
Afluzole Oral Suspension contains Fluconazole. Afluzole uses:
Afluzole Oral Suspension is indicated in
Afluzole Oral Suspension contains Fluconazole 50 mg/5 ml. Afluzole doses:
Adult & child:
Invasive candidal infections including candidaemia and disseminated candidiasis and cryptococcal infections including meningitis, by IV, 400 mg initially then 200 mg daily, increased if necessary to 400 mg daily, treatment continued according to response (at least 6-8 weeks for cryptococcal meningitis); Child 6-12 mg/kg daily (every 72 hours in neonate up to 2 weeks old, every 48 hours in neonate 2-4 weeks old); maximum 400 mg daily.Prevention of relapse of cryptococcal meningitis, by IV, 100-200 mg daily.
Since oral absorption is rapid and almost complete, the daily dose of Afluzole Oral Suspension is the same for oral and intravenous administration.
Therapy with Afluzole Oral Suspension is well tolerated. The common adverse effects are nausea. abdominal pain, vomiting, diarrhoea, headache and skin rash.
Afluzole Oral Suspension is the first of a new subclass of synthetic triazole antifungal agent which acts by inhibition of the ergosterol component of the fungal cell membrane. It is active against a broad spectrum of fungal pathogens and is available for oral use.
Caution should be taken in renal impairment, pregnancy and breast feeding and in raised liver enzymes. The use of Afluzole Oral Suspensionin lactating mothers is not recommended.
Rifampicin reduces plasma concentration of Afluzole Oral Suspension. Afluzole Oral Suspension enhances the effect of nicoumalone, warfarin and phenytoin. It also increases the plasma concentration of sulphonylureas & theophlline.
Use in pregnancy: Afluzole Oral Suspension should be used in pregnancy only if the potential benefit justifies the possible risk to the foetus.Use in lactation: Afluzole Oral Suspension is secreted in human milk at concentrations similar to plasma. Therefore, the use of Flouconazole in nursing mother is not recommended.
Afluzole Oral Suspension is contraindicated to patients hypersensitive to this drug and in advanced liver disease.
Store below 30° C. Protect from light & moisture. Remaining reconstituted suspension should not be used after 7 days. If it is kept under freezing temperature (2- 8° C) , it can be used for 14 days. Keep out of the reach of children.
In the case of an overdose, supportive measures should be instituted.
Afluzole Oral Suspension price in Bangladesh 109.62