Adryl Syrup

Brand Name: Adryl
Generic: Diphenhydramine Hydrochloride
Weight: 10 mg/5 ml
Type: Syrup
Therapeutic Class: Sedating Anti-histamine
Manufacturer: Square Pharmaceuticals Ltd.
Price: 49.00
Last Updated: 2020-11-22 18:15:00

Adryl Syrup Uses

Adryl Syrup contains Diphenhydramine Hydrochloride. Adryl uses:

Diphenhydramine is indicated for the treatment of followings:

  • Seasonal, perennial, vasomotor rhinitis
  • Urticaria, angioneurotic oedema, anaphylaxis
  • Pruiritic conditions
  • Premedication for emesis and motion sickness
  • Miscellaneous like meniere's disease and parkinsonism

Adryl Syrup Doses

Adryl Syrup contains Diphenhydramine Hydrochloride 10 mg/5 ml. Adryl doses:

Adult-

  • Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.

Children-

  • 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
  • More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day

 

Side Effects

Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.

Introduction

Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.

Adryl Precaution

Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.

Interaction

Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.

Pregnancy Lactation use

Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.

Contraindication

Known hypersensitivity to Diphenhydramine Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.

Special Warning

 

Acute Overdose

Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical). 

Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.

Interaction with other Medicine

 

Storage Condition

Store between 15-30° C. Protect from moisture.

Adryl Syrup price in Bangladesh 49.00