Adnix Tablet

Brand Name: Adnix
Generic: Nitazoxanide
Weight: 500 mg
Type: Tablet
Therapeutic Class: Anti-diarrhoeal Antiprotozoal
Manufacturer: Alco Pharma Ltd.
Price: 14.00
Last Updated: 2020-11-21 18:15:00
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Adnix Tablet Uses

Adnix Tablet contains Nitazoxanide. Adnix uses:

Adnix Tablet is indicated in diarrhoea caused by Cryptosporidium parvum and Giardia lamblia, Amebiasis and helminth infections.

Adnix Tablet Doses

Adnix Tablet contains Nitazoxanide 500 mg. Adnix doses:

Age 1-3 years: 5 ml (100 mg) twice daily for 3 days

Age 4-11 years: 10 ml (200 mg) twice daily for 3 days

Age >12 years: 25 ml or 1 tablet (500 mg) twice daily for 3 days

The suspension or tablet should be taken with food.

30 ml suspension: Shake the bottle well before adding water. Then add 20 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 30 ml suspension.

60 ml suspension: Shake the bottle well before adding water. Then add 40 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 60 ml suspension.

Side Effects

Adnix Tablet is generally well tolerated. However abdominal pain, diarrhoea vomiting and headache have been reported rarely

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Introduction

Adnix Tablet, a synthetic antiprotozoal agent. Adnix Tablet is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.

Adnix Precaution

Adnix Tablet should be administrated with caution to patients with hepatic, renal and biliary disease.

Interaction

Adnix Tablet is highly bound to plasma protein (>99.9%). Therefore, caution should be used when administering Adnix Tablet concurrently with other highly plasma-protein bound drugs.

Pregnancy Lactation use

Pregnancy category B. This drug should be used during pregnancy only if clearly needed.

Nursing mother: It is not known whether Adnix Tablet is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Adnix Tablet is administrated to a nursing woman.

Contraindication

Known hypersensitivity to Adnix Tablet or any other ingredient in the formulations

Special Warning

Paediatric Use: Safety and effectiveness of Adnix Tablet for Oral Suspension in paediatric patients less than one year of age have not been studied.

Impaired renal or hepatic function: The pharmacokinetics of Adnix Tablet in patients with impaired renal or hepatic function have not been studied. Therefore, Adnix Tablet must be administered with caution to patients with hepatic and biliary disease, to patients with renal disease and to patients with combined renal and hepatic disease.

Acute Overdose

Information on Adnix Tablet overdosage is not available. Single oral doses of up to 4000 mg Adnix Tablet have been administered to healthy adult volunteers without significant adverse effects.

Interaction with other Medicine

 

Storage Condition

Store in a cool and dry place, away from light and moisture. Once reconstituted suspension should be used within 7 days.

Adnix Tablet price in Bangladesh 14.00

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