Acron Tablet

Brand Name: Acron
Generic: Buprenorphine
Weight: 200 mcg
Type: Tablet
Therapeutic Class: Opioid analgesics
Manufacturer: ACI Limited.
Price: 14.10
Last Updated: 2020-11-22 18:15:00

Acron Tablet Uses

Acron Tablet contains Buprenorphine. Acron uses:

Buprenorphine is indicated for Moderate to severe pain, Anaesth premed, Opioid dependence, Anaesth premed, Perioperative analgesia

Acron Tablet Doses

Acron Tablet contains Buprenorphine 200 mcg. Acron doses:


  • Oral: Sublingual Moderate to severe pain: 200-400 mcg 6-8 hourly.
  • IV: Perioperative analgesia: 300-450 mcg via slow inj.
  • IV/IM: Moderate to severe pain: 300-600 meg 6-8 hourly.
  • IM: Anesthesia premed: 300 meg.

Severe hepatic Impairment: Dose adjustment needed.


Side Effects

Common side effects are CNS depression, including somnolence, dizziness, alterations in judgment and levels of consciousness, including coma; sedation, dizziness, sweating, vertigo, headache; nausea, vomiting, dry mouth, constipation, dyspepsia, abdominal cramps, flatulence, diaphoresis; rash, urticaria, pruritus; miosis, blurred vision, hallucinations and other psychotomimetic effects; hypotension leading to syncope, HTN, tachycardia, bradycardia, ECG abnormalities.


Buprenorphine exerts its analgesic effect via high affinity binding to the μ-opioid receptors in the CNS. It displays partial μ-opioid agonist activity and weak kappa antagonist activity.

Acron Precaution

Patient with pulmonary impairment or compromised respiratory iratory function (e.g. COPD, cor pulmonale, decreased respiratory reserve, hypoxia, hypercapnia, pre-existing respiratory depression). Patient with hypothyroidism, myxedema, adrenocortical insufficiency (e.g. Addison's disease), dysfunction of biliary tract including acute pancreatitis, acute alcoholism, delirium tremens, toxic psychoses, kyphoscoliosis, prostatic hypertrophy or urethral stricture; comatose patients. Patient with CNS depression, history of seizure disorders, head injury, intracranial lesions or conditions in which intracranial pressure may be increased. Patient with personal or family history of QT interval prolongation, hypokalaemia or unstable cardiac disease (e.g. AF, CHF, myocardial ischaemia), particularly in transdermal admin. Hepatic or renal impairment. Pregnancy and lactation.


Plasma-buprenorphine concentrations may be affected when co-administered with drugs that induce or inhibit CYP3A4 isoenzyme. Enhanced depressant effects of other CNS depressants, other opiate agonists, anaesth, antihistamines, muscle relaxants, tranquilisers (e.g. phenothiazines), sedatives and hypnotics (e.g. benzodiazepines). Increased and/or prolonged activity with drugs that may reduce hepatic blood flow (e.g. halothane). Receiving class IA (e.g. quinidine, procainamide) or class III (e.g. sotalol, amiodarone) antiarrhythmic agents with transdermal buprenorphine may increase the risk of QT interval prolongation.

Pregnancy Lactation use

Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.


Transdermal: Patient with known or suspected paralytic ileus, substantial respiratory depression or severe bronchial asthma. Management of acute, intermittent, mild, or short-term (including post-op) pain. Concomitant admin of IV buprenorphine and oral diazepam. Concurrent use or w/in 14 days of discontinuation of MAOIs.

Special Warning


Acute Overdose

Symptoms: Resp depression, sedation, somnolence, nausea, vomiting, CV collapse and marked miosis. 

Management: Supportive treatment. May use naloxone or resp stimulants if appropriate.

Interaction with other Medicine


Storage Condition

Store between 15-30° C. Protect from prolonged exposure to light. Avoid freezing.

Acron Tablet price in Bangladesh 14.10