|Brand Name:||Acme's Dextrose DS|
|Therapeutic Class:||Intravenous fluid preparations, Parenteral Nutritional preparations|
|Manufacturer:||Acme Laboratories Limited.|
|Last Updated:||2020-11-21 18:15:00|
Acme's Dextrose DS IV Infusion contains Dextrose. Acme's Dextrose DS uses:
Dextrose is administered as a parenteral nutrition solution in the treatment of carbohydrate depletion and hypoglycaemic coma. Because of its high dextrose content it is used in the treatment of cerebral edema, shock, circulatory collapse, unconsciousness and to correct hyperkalaemia with or without insulin.
Acme's Dextrose DS IV Infusion contains Dextrose 10% w/v. Acme's Dextrose DS doses:
The volume and rate of infusion of dextrose solution will depend upon the requirements of the individual patient and the judgement of the physician.
The maximum rate at which dextrose can be infused without producing glycosuria is 0.5 gm/kg/hr.
The usual recommended flow rate for adult is 10-35 drops per minute infused intravenously.
It should not be administered by SC or IM route. Dextrose should be infused through the largest available peripheral vein.
Venous thrombosis, phlebitis, hypovolemia, hypervolemia, dehydration, oedema, fever, mental confusion, unconsciousness, hyperosmolar syndrome, hyperglycaemia, hypokalaemia, acidosis, hypophosphataemia, hypomagnesemia, polyuria, glycosuria, ketonuria, nausea, diarrhoea, polydipsia, vein irritation, tissue necrosis, pulmonary oedema, tachypnoea.
Dextrose is a monosaccharide that is used as a source of calories and water for hydration. It helps to reduce loss of body protein and nitrogen. It also promotes glycogen deposition in the liver. When used with insulin, it stimulates the uptake of potassium by cells, especially in muscle tissue, thus lowering serum potassium levels.
Concentrated dextrose solution should not be infused rapidly or for a long period. It may be hazardous in patients with impaired hepatic or renal function and severe sepsis.
Care should be taken to avoid circulatory overload, particularly in patients with cardiac insufficiency. Caution must be exercised in the administration of these injections to patients receiving corticosteroids or corticotropin. These injections should be used with caution in patients with overt or subclinical diabetes mellitus.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. Do not administer unless solution is clear and seal is intact.
There is no drug drug interaction and none well documented.
Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Concentrated dextrose solution is contraindicated in patients with Glucose-Galactose Malabsorption Syndrome and severe hydration. The infusion of hypertonic dextrose injections is contraindicated in patients having intracranial or intraspinal hemorrhage, in patients who are severely dehydrated, in patients who are anuric, and in patients in hepatic coma. Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Reevaluate patient's condition and institute appropriate symptomatic treatment.
Store at 25°C.
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