Aclene Plus Gel

Brand Name: Aclene Plus
Generic: Adapalene + Benzoyl peroxide
Weight: 0.1% + 2.5%
Type: Gel
Therapeutic Class: Topical retinoid and related preparations
Manufacturer: Drug International Ltd.
Price: 210.00
Last Updated: 2020-11-21 18:15:00

Aclene Plus Gel Uses

Aclene Plus Gel contains Adapalene + Benzoyl peroxide. Aclene Plus uses:

Adapalene + Benzoyl peroxide is indicated for the topical treatment of acne vulgaris.

Aclene Plus Gel Doses

Aclene Plus Gel contains Adapalene + Benzoyl peroxide 0.1% + 2.5%. Aclene Plus doses:

Persons 12 years of age and older apply a thin film of Adapalene + Benzoyl peroxide to affected areas of the face and/or trunk once daily after washing. Use a pea-sized amount for each area of the face (e.g. forehead, chin, each cheek). Avoid the eyes, lips and mucous membranes. Adapalene + Benzoyl peroxide is not for oral, ophthalmic, or intravaginal use.

Pediatric Use: Safety and effectiveness of Adapalene + Benzoyl peroxide in pediatric patients under the age of 12 have not been established.

 

Side Effects

Adapalene + Benzoyl peroxide is usually a well tolerated preparation. But the local adverse reactions that may be observed are dry skin, erythema, pruritus of skin, skin scaling, skin rash etc.

Introduction

Adapalene + Benzoyl peroxide is a combination product for topical use containing Adapalene (a synthetic retinoid) and Benzoyl peroxide.

Adapalene

Adapalene binds to specific retinoic acid nuclear receptors but does not bind to cytosolic receptor protein. Biochemical and pharmacological profile studies have demonstrated that Adapalene is a modulator of cellular differentiation, keratinization and inflammatory processes. However, the significance of these findings with regard to the mechanism of action of Adapalene for the treatment of acne is unknown.

Benzoyl peroxide

Benzoyl peroxide has sebostatic and keratolytic activity counteracting the hyperkeratinisation and excessive sebum secretion associated with acne vulgaris. It has antibacterial activity against Propionibacterium acnes, the organism implicated in acne vulgaris.

Aclene Plus Precaution

Exposure to sunlight (ultraviolet ray), including sunlamps, should be minimized during the use of this preparation. Use of sunscreen products and protective apparel, (e.g. hat) are recommended when exposure cannot be avoided. Weather extremes, such as wind or cold, may be irritating to patients under treatment with Adapalene + Benzoyl peroxide.

Interaction

Concomitant topical acne therapy should be used with caution because a possible cumulative irritancy effect may occur, especially with the use of peeling, desquamating, or abrasive agents. No formal drug-drug interaction studies were conducted.

Pregnancy Lactation use

Pregnancy: Pregnancy category C. There are no well-controlled trials in pregnant women treated with Adapalene + Benzoyl peroxide.

Lactating mother: It is not known whether Adapalene or Benzoyl peroxide is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Adapalene + Benzoyl peroxide is administered to a lactating mother.

Contraindication

Should not be administered to individuals who are hypersensitive to any of its component.

Special Warning

Safety and effectiveness of Adapalene and Benzoyl peroxide gel in pediatric patients under the age of 12 years have not been established.

Acute Overdose

No available data are found.

Interaction with other Medicine

Particular caution should be exercised in using preparations containing sulfur, resorcinol or salicylic acid in combination with this preparation. If these preparations have been used, it is advisable not to start therapy with Adapalene + Benzoyl peroxide until the effects of such preparations in the skin have subsided.

Warning: Adapalene + Benzoyl peroxide should be discontinued if hypersensitivity to any of the ingredients is noted. Patients with sunburn should be advised not to use the product until fully recovered.

Storage Condition

Store in a cool (below 25°C) and dry place protected from light and moisture. Keep out of the reach of children. Keep the tube tightly closed after use.

Aclene Plus Gel price in Bangladesh 210.00