Acflam

Acflam Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Acflam is a brand name. Its generic name is Aceclofenac.

Introduction

Acflam is a non-steroidal anti-inflammatory drug (NSAID) used to manage pain, swelling, and inflammation due to various medical conditions. It is the racemic mixture of the two forms of a compound. It was developed in 1968 and approved for medical use in 1993.

Uses

Acflam is used to treat symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used in the treatment of musculoskeletal disorders, such as neck and back pain, sports injuries, sprains and strains, tendinitis, and bursitis.

Mechanism of Action

Acflam works by blocking the production of prostaglandins, hormones that cause inflammation and pain. By blocking this action, it reduces the pain and inflammation caused by these conditions.

How Long Does It Take to Work?

Acflam typically takes up to 2 weeks for its effect to be fully manifested. However, most patients experience relief within a few days.

Absorption

Acflam is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the urine and feces.

Route of Elimination

Acflam is secreted in the urine and feces. It is also partially metabolized by the liver.

Dosage

Acflam is available in 50 mg, 100 mg, and 200 mg doses. The recommended dose is one to two tablets taken orally every 8-12 hours as needed for pain relief. The maximum daily dose is 800 mg per day. The dose may be increased or decreased based on individual response and tolerance.

Administration

Acflam tablets should be taken orally, with or without food, as directed by your doctor. The tablets should be swallowed whole and should not be chewed or crushed.

Side Effects

Common side effects of Acflam include gastrointestinal discomfort, nausea, headache, dizziness, and rash. Serious side effects include difficulty breathing, chest pain, and liver or kidney problems. Contact your doctor if you experience severe or persistent side effects.

Toxicity

Acflam is generally well-tolerated, however, overdoses can result in serious toxicity. Symptoms of overdose include blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Precaution

Acflam should be taken with caution if you have a history of kidney, liver, or gastrointestinal disorder, asthma, dehydration, or blood clotting disorder. You should also avoid taking alcohol or other medications that can irritate the stomach while taking aceclofenac.

Interactions

Acflam may interact with certain other medications. Be sure to inform your doctor of any medications, supplements, or vitamins you are currently taking. This medication may also interact with other medical conditions or lifestyle choices.

Drug Interactions

Acflam can interact with certain other medications, including anti-inflammatory drugs, antidepressants, blood thinners, antibiotics, antifungal medications, and vitamin supplements. Be sure to tell your doctor and pharmacist about all medications you are currently taking, including any over-the-counter medications.

Food Interactions

Acflam may interact with certain foods. It is important to talk to your doctor about any dietary restrictions or food interactions that may occur when taking this medication.

Pregnancy Use

Acflam should not be used during pregnancy as it may cause harm to the fetus. Women who are pregnant or planning to become pregnant should not take this medication.

Lactation Use

Acflam should not be used during lactation as it may be secreted into breast milk. Women who are breastfeeding should not take this medication.

Acute Overdose

Overdose of aceclofenac can be potentially life-threatening. Symptoms of overdose include, blurred vision, difficulty breathing, confusion, seizures, and coma. Seek immediate medical attention if you or someone you know has overdosed on this medication.

Contraindication

Acflam should not be used in people with a history of stomach or intestinal ulcer, liver and kidney disease, and patients with a history of hypersensitivity to other drugs including Acflam.

Use Direction

Acflam should be taken exactly as prescribed by your doctor. Do not take more or less of the medication than directed. Do not take the medication more or less frequently than directed.

Storage Condition

Acflam should be stored at room temperature, away from light, moisture, and heat. Keep away from children and pets.

Volume of Distribution

Acflam has a large volume of distribution and is widely distributed throughout the body.

Half Life

The elimination half-life of aceclofenac is approximately 6 hours.

Clearance

Acflam is cleared from the body primarily by the kidneys. The oral clearance of the drug is approximately 40 mL/min.

Here you find in details version of Acflam

Some Frequently Asked Questions About Acflam

What is Acflam?

Acflam is a non-steroidal anti-inflammatory drug (NSAID) used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

What is the mechanism of action of Acflam?

Acflam is thought to work by inhibiting the activity of the enzyme cyclooxygenase (COX). Inhibition of COX leads to decreased synthesis of pro-inflammatory and painmediating prostaglandins, resulting in a reduction in inflammation and pain.

What is the dosage of Acflam?

The recommended adult dose of Acflam is 100 to 200 mg twice daily or as directed by the physician.

What are the side effects of Acflam?

The common side effects of Acflam include stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

What should be avoided while taking Acflam?

Alcohol should be avoided while taking Acflam as it can increase the risk of stomach ulcers and bleeding. ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids should also be avoided while taking Acflam.

Can Acflam be used for migraine?

Acflam is not usually recommended for the treatment of migraine headaches, although some patients may find it to be effective. Patients should discuss this with their doctor to determine if Acflam is an appropriate treatment.

Can I take Acflam with paracetamol?

Yes, it is safe to take Acflam with paracetamol. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Can I take Acflam during pregnancy?

Acflam is not recommended during the first and third trimester of pregnancy. There is limited data on its use and safety during the second trimester of pregnancy, and it should be used only if the potential benefits outweigh the risks.

Is Acflam a muscle relaxant?

No, Acflam is not a muscle relaxant. It is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Acflam be used for headaches?

Acflam is not usually recommended for the treatment of headache. Patients should discuss this with their doctor to determine if Acflam is an appropriate treatment.

What are the serious side effects of Acflam?

Serious side effects of Acflam include signs of allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), chest pain, increased blood pressure, shortness of breath, and bloody or black, tarry stools.

What is the difference between Acflam and Ibuprofen?

Acflam and ibuprofen are both non-steroidal anti-inflammatory drugs (NSAIDs) used for reducing pain and inflammation. The main difference between them is that Acflam is thought to have fewer gastrointestinal side effects than ibuprofen.

Can I take Acflam if I have high blood pressure?

Yes, you can take Acflam if you have high blood pressure. However, it is important to follow the dosages as prescribed by your doctor, and not to exceed the recommended dosages.

Is Acflam safe?

Acflam is generally safe and well-tolerated when taken at prescribed doses. However, it can cause side effects such as stomach upset, heartburn, nausea, vomiting, diarrhea, drowsiness, headache, constipation, joint pain, rash and itching.

Can Acflam be used to treat fever?

No, Acflam is not usually recommended for the treatment of fever. It is used to reduce pain and inflammation associated with conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

How long does Acflam take to work?

Acflam usually starts to work within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

Can I take Acflam with warfarin?

No, it is not recommended to take Acflam with warfarin as it could increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Acflam.

What is the maximum daily dose of Acflam?

The maximum daily dose of Acflam is 400 mg per day. Higher doses are not recommended and patients should not exceed the recommended dose.

Is Acflam available over the counter?

No, Acflam is a prescription medication available only through a doctor's prescription.

Is Acflam a strong painkiller?

Acflam is a medium strength painkiller used for treating pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Can Acflam be used to treat gout?

Yes, Acflam can be used to treat gout. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Can Acflam be taken with food?

Yes, it is generally recommended to take Acflam with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

Can I take Acflam before surgery?

No, it is not recommended to take Acflam before surgery as it may increase the risk of bleeding. You should discuss this with your doctor before taking this medication.

What should be done in case of an overdose?

If an overdose of Acflam is suspected then medical attention should be sought immediately. Symptoms of an overdose may include nausea, vomiting, dizziness, abdominal pain, and drowsiness.

What precautions should I take while using Acflam?

It is important to follow all the instructions and precautions provided by the doctor while taking Acflam. It is also important to keep your doctor updated about any medical conditions you have and be aware of any medications, supplements, or herbal remedies you are taking that could interact with Acflam.

What drug interactions can occur when taking Acflam?

Acflam may interact with certain drugs, such as ACE inhibitors, anticoagulants, diuretics, NSAIDs, and corticosteroids. It is important to discuss with your doctor any medications, supplements, or herbal remedies you are taking, to prevent any potential drug interactions.

Is Acflam safe for long-term use?

Acflam is generally safe when taken for a short period of time. Long-term use of Acflam can increase the risk of side effects, such as gastrointestinal bleeding, increased risk of heart attack, stroke, and kidney damage. If you are taking Acflam for a long-term period, it is important to discuss this with your doctor.

Can Acflam cause anemia?

Yes, long-term use of Acflam can cause anemia due to decreased production of red blood cells. If you are taking Acflam for long-term use, it is important to discuss with your doctor about the potential risks of anemia.

Can Acflam cause liver damage?

Yes, Acflam can cause liver damage in rare cases. If you experience any signs of liver damage such as yellowing of the eyes or skin, dark urine, or abdominal pain, you should seek medical attention immediately.

Can Acflam cause kidney damage?

Yes, long-term use of Acflam can cause kidney damage in rare cases. If you experience any signs of kidney damage such as decreased urination, nausea, vomiting, or fluid retention, you should seek medical attention immediately.

Can Acflam cause weight gain?

No, Acflam does not usually cause weight gain. However, it is possible for certain side effects, such as abdominal pain, nausea, and vomiting, to lead to decreased appetite and weight loss.

Can I take Acflam with aspirin?

No, it is not recommended to take Acflam with aspirin as it may increase the risk of stomach ulcers and bleeding. If you are taking aspirin then you should discuss this with your doctor before taking Acflam.

Can I take Acflam for menstrual cramps?

Yes, Acflam can be used to treat mild to moderate menstrual cramps. However, it is important to follow the dosage as prescribed by the doctor and not to exceed the recommended dosage.

Does Acflam cause drowsiness?

Yes, Acflam may cause drowsiness. If you experience drowsiness after taking this medication then it is important to avoid activities that require alertness such as driving or operating machinery.

Does Acflam interact with warfarin?

Yes, Acflam can interact with warfarin and increase the risk of bleeding. If you are taking warfarin then you should discuss this with your doctor before taking Acflam.

What is the onset of action of Acflam?

The onset of action of Acflam is usually within a few hours of taking it. Maximum effects are usually seen within 1-2 weeks.

How long does Acflam take to work?

The effects of Acflam may take a few hours to be felt. Maximum effects are usually seen within 1-2 weeks.

Is Acflam safe for children?

Acflam is not recommended for use in children under 12 years of age. If a child needs to take this medication then it should be taken only under the supervision of a doctor.

Can Acflam be taken with food?

Yes, it is generally recommended to take Acflam with food or after meals to reduce the risk of stomach upset. It is important to follow your doctor's instructions when taking this medication.

What is the half-life of Acflam?

The half-life of Acflam is approximately 8 to 12 hours.

Is Acflam addictive?

No, Acflam is not addictive.

Can I take Acflam if I have asthma?

Yes, you can take Acflam if you have asthma. However, it is important to discuss this with your doctor to ensure that Acflam is