Acerux-H

Acerux-H Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Acerux-H is a brand name. Its generic name is Acyclovir + Hydrocortisone.

Introduction

Acyclovir+ Hydrocortisone is a combination medication used to treat herpes/shingles infections of the skin. It contains the antiviral drug acyclovir and the steroid hydrocortisone. Acyclovir works by stopping the growth of the virus while hydrocortisone reduces inflammation and itching. It is available as an ointment and can be used in adults, adolescents, and children.

Uses

  • Treating shingles (herpes zoster) and herpes cold sores (infection of the lips and mouth).
  • Relieving itching and inflammation caused by these conditions.

Mechanism of Action

Acyclovir works by inhibiting the replication of the viral genome in the infected cell. Hydrocortisone belongs to the group of medicines called steroids. It works by blocking the body's inflammatory response and restricting the production of chemicals that make the skin red and itchy. The combined properties of these two drugs reduce the pain, itching, and severity of the infection.

How Long Does It Take To Work?

Acyclovir+ Hydrocortisone usually begins to show improvement within 1 to 2 days of starting medication. Some people may experience faster relief of symptoms, while others may take a little longer.

Absorption

Acyclovir+ Hydrocortisone is a topical ointment. It is absorbed through the skin and is not systemically absorbed. It acts locally on the area where it is applied.

Route of Elimination

Acyclovir+ Hydrocortisone is not systemically absorbed and therefore does not have a route of elimination. It works locally on the area where it is applied and is eliminated through the normal process of shedding skin cells.

Dosage

Acyclovir+ Hydrocortisone is available in a 5%/1% ointment. It is applied to the affected area 2-3 times a day for 5-7 days, or as directed by your doctor.

Administration

Acyclovir+ Hydrocortisone ointment should be applied to the affected area. It should be massaged in until it is completely absorbed. Wash your hands immediately after application. Do not bandage or cover the treated area.

Side Effects

Common side effects of Acyclovir+ Hydrocortisone are skin irritation, itching, burning, and dryness. If these effects become severe or continue for more than a week, contact your doctor.

Toxicity

Acyclovir+ Hydrocortisone is generally considered to be safe. In rare cases, it may cause skin irritation or an allergic reaction. If you experience any symptoms of a severe allergic reaction, seek medical attention immediately.

Precautions

  • Do not use the ointment if your skin is broken or irritated.
  • Do not use Acyclovir+ Hydrocortisone on a child without consulting a doctor.
  • Do not use this medication to treat any condition other than that for which it was prescribed.
  • Avoid contact with eyes, nose, and other mucous membranes.
  • Do not apply to open wounds or infected skin.

Interaction

Acyclovir+ Hydrocortisone may interact with other drugs. Tell your doctor about all prescription, non-prescription, and herbal medications that you are taking. Make sure your doctor is aware of all medications you are taking before starting treatment with Acyclovir+ Hydrocortisone.

Disease Interaction

Acyclovir+ Hydrocortisone should not be used if you have a known hypersensitivity to acyclovir or hydrocortisone. Tell your doctor if you have any other medical conditions, especially diabetes, eczema, fungus infection, herpes simplex infection, or are pregnant or breastfeeding before using Acyclovir+ Hydrocortisone.

Drug Interaction

Acyclovir+ Hydrocortisone may interact with some drugs such as antifungal medications, probenecid, and sulfonamides. Tell your doctor about all the drugs you take before starting treatment with Acyclovir+ Hydrocortisone.

Food Interactions

Acyclovir+ Hydrocortisone is usually taken topically. Avoid applying it to the skin around the mouth. No food interactions have been reported with this drug.

Pregnancy Use

The safety of Acyclovir+ Hydrocortisone during pregnancy has not been established. Consult your doctor before using this medication if you are pregnant.

Lactation Use

Acyclovir+ Hydrocortisone has not been evaluated for its use in lactation. Consult your doctor before using this medication if you are breastfeeding.

Acute Overdose

If an overdose occurs, seek emergency medical attention. Signs and symptoms of acute overdose may include skin irritation, redness, and burning sensation.

Contraindication

Acyclovir+ Hydrocortisone ointment should not be used if you have a known hypersensitivity to acyclovir or hydrocortisone. Tell your doctor if you have any other medical conditions, especially diabetes, eczema, fungus infection, herpes simplex infection, or are pregnant or breastfeeding before using Acyclovir+ Hydrocortisone.

Use Direction

Acyclovir+ Hydrocortisone should be applied to the affected area 2-3 times a day (onym twice a day in children) for 5-7 days, or as directed by your doctor. Wash your hands immediately after application. Do not bandage or cover the treated area.

Storage Conditions

Store Acyclovir+ Hydrocortisone in a cool, dry place, away from direct sunlight, and out of reach of children.

Volume of Distribution

Acyclovir+ Hydrocortisone is not systemically absorbed and therefore does not have a volume of distribution. It works locally on the area where it is applied and is not distributed systematically throughout the body.

Half Life

Acyclovir+ Hydrocortisone does not have a known or estimated half-life since it is not systemically absorbed and is eliminated through normal skin shedding.

Clearance

Acyclovir+ Hydrocortisone is not systemically absorbed and therefore does not have a clearance. It works locally on the area where it is applied and is eliminated through the normal process of shedding skin cells.

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