A-Rox Powder for Suspension


Generic: Roxithromycin
Weight: 50 mg/5 ml
Price: 63.24
Manufacturer: Ambee Pharmaceuticals Ltd.
Last Updated: 2020-08-11 18:15:00

A-Rox Powder for Suspension Uses

A-Rox Powder for Suspension contains Roxithromycin. A-Rox Powder for Suspension is used for:

A-Rox Powder for Suspension is indicated in the treatment of infections caused by susceptible microorganisms;

Respiratory infections like pneumonia, acute and chronic bronchitis, and bronchopneumonia

ENT infections like tonsillitis, pharyngitis, sinusitis and otitis media.

Skin infections like folliculitis, furuncles, cellulitis, carbuncles, pyoderma, impetigo and infected dermatitis.

Genital infections like urethritis, prostatitis, cervicitis and salpingitis especially if produced by Chlamydia trachomatis.

A-Rox Powder for Suspension, is a macrolide with antibacterial properties similar to erythromycin. It is active against Gram-positive bacteria like staphylococci, streptococci, listeria, corynebacteria; Gram-negative bacteria such as gonococci, Haemophilus influenzae, Haemophilus ducreyi, Legionella, campylobacter, and atypical pathogens like Mycoplasma and Chlamydia. A-Rox Powder for Suspension has been found useful in the treatment of upper and lower respiratory tract infection, otorhinolaryngological, skin, dental and genital infections. It is well tolerated by adults and children.

 

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Generic

Introduction

A-Rox Powder for Suspension inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.

Therapeutic Class

Macrolides

A-Rox Powder for Suspension Doses

Adult dose: The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days. A-Rox Powder for Suspension is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily.

Pediatric dose: The dose for children is 2.5 to 5 mg/kg body weight twice a day. The following general guidelines can be followed

  • 6 to 11 Kg: 25 mg A-Rox Powder for Suspension 12 hourly.
  • 12 to 23 Kg: 50 mg A-Rox Powder for Suspension 12 hourly.
  • 24 to 40 Kg: 100 mg A-Rox Powder for Suspension 12 hourly.

A normal course of therapy is between 5 and 10 days.

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Administrations

A-Rox Powder for Suspension Side Effects

A-Rox Powder for Suspension is well tolerated by patients of all age groups. Less than 4% of treated patients complain of side effects mainly nausea, abdominal pain, diarrhoea and hypersensitivity rash. Other side effects reported include vomiting, dizziness, headache, pruritus, dyspepsia, flatulence, tinnitus, vertigo and constipation. These are in general minor and do not necessitate withdrawal of therapy.

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Precaution

A-Rox Powder for Suspension should not be used in patients with a history of hypersensitivity to the drug. In patients with hepatic diseases the dose of A-Rox Powder for Suspension should not exceed 150 mg twice a day.

Interaction

A-Rox Powder for Suspension does not have any affinity for cytochrome P-450 binding sites and thus is unlikely to produce drug interaction mediated by this enzymatic system. A-Rox Powder for Suspension shows mild interaction with theophylline though this has not been found to produce clinically relevant effects. Alteration in the pharmacokinetics of carbamazepine or warfarin has not been found. Antacids, H2- receptor antagonists and food has no effect on the absorption of A-Rox Powder for Suspension.

A-Rox Powder for Suspension Uses During Pregnancy

The safety of A-Rox Powder for Suspension in pregnancy has not been established. It appears in breast milk in small amounts and dose not produce adverse effects in the breast fed infant.

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Accute Overdose

 

Contraindication

A-Rox Powder for Suspension should not be administered simultaneously with ergotamine or its derivatives as it may provoke arterial spasm and severe ischaemia.

Uses Direction

 

Storage Condition

 

Special Warning

 

Interactions with other Medicine

 

A-Rox Powder for Suspension price in Bangladesh 63.24