A-Phyline

A-Phyline Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? A-Phyline is a brand name. Its generic name is Aminophylline.

A-Phyline

A-Phyline is a bronchodilator and anti-inflammatory drug used to treat chronic obstructive pulmonary diseases (COPD). It works by relaxing the muscles in the lungs, allowing them to receive the oxygen they need. A-Phyline is also used to treat wheezing, shortness of breath, and chest tightness associated with asthma and other lung diseases.

Uses For

A-Phyline is used in the treatment of chronic obstructive pulmonary diseases (COPD) and asthma. It can also be used to reduce the risk of a heart attack during a period of physical exertion, such as running or exercising, as it helps to keep the heart rate and blood pressure under control.

Mechanism Of Action

A-Phyline works by relaxing the muscles that surround the airways in the lungs, allowing them to open and get more oxygen to the lungs. It also has anti-inflammatory properties that can reduce airway inflammation and swelling. These combined effects help to reduce symptoms of respiratory disorders such as wheezing, coughing, and shortness of breath.

How Long Does It Take to Work?

A-Phyline usually takes effect within 30 minutes of taking the medicine. Some people may notice an effect sooner, while others may take up to two hours to feel the benefit.

Absorption

A-Phyline is absorbed quickly in the gastrointestinal tract and reaches peak concentrations in the blood after 1 to 2 hours. The absorption is not affected by food.

Route Of Elimination

A-Phyline is eliminated mainly by the kidneys, but also by the liver, gastrointestinal tract, and lungs. About 50 to 85% of the drug is excreted unchanged in the urine.

Dosage

The recommended dose of aminophylline varies depending on age, weight, and the severity of the condition being treated. Usually, it is given by mouth 3 to 4 times a day. The dose may be increased or decreased depending on the response of the patient.

Administration

A-Phyline should be taken orally, with a full glass of liquid. It should never be taken in larger or smaller amounts than directed by your doctor. The drug should be taken at evenly spaced intervals, such as every 6 to 8 hours.

Side Effect

Common side effects of aminophylline include: nausea, vomiting, diarrhea, headache, dizziness, difficulty sleeping, and mild skin rash or itching. More serious side effects include: rapid heartbeat, chest pain, blindness, coma, fainting, and seizures.

Toxicity

A-Phyline is toxic in high doses, and can cause serious side effects. Overdose symptoms include irregular heartbeat, nausea, seizures, and death. It is important to take only the recommended dose and not to change the dosage without consulting your doctor.

Precaution

A-Phyline should be used with caution in patients with a history of heart disease, diabetes, high blood pressure, thyroid problems, or seizure disorders. It should not be used by pregnant or nursing women, as it may pass into breast milk and could potentially harm an unborn child or nursing baby.

Interaction

A-Phyline may interact with other medications, such as antibiotics, sedatives, painkillers, and antibiotics. It is important to tell your doctor if you are using any other medications before taking aminophylline.

Disease Interaction

A-Phyline may interact with certain diseases. People who have heart disease, high blood pressure, or asthma should be monitored closely while taking the medication, as it may worsen these conditions. People with diabetes should have their blood sugar levels checked regularly.

Drug Interaction

A-Phyline may interact with certain drugs, such as antibiotics, sedatives, painkillers, and antibiotics. This can cause an increase in side effects, or the drugs may not work as well. It is important to tell your doctor if you are taking any other drugs before taking aminophylline.

Food Interaction

A-Phyline may interact with certain foods, such as coffee, chocolate, and certain fruits and vegetables. These foods may increase the risk of side effects, or the medications may not work as well. It is important to talk to your doctor before eating these foods while taking aminophylline.

Pregnancy Use

A-Phyline should not be used during pregnancy unless absolutely necessary. It may pass into breast milk and could potentially harm an unborn child or nursing baby. If you are pregnant or lactating, it is important to talk to your doctor about the risks of taking aminophylline.

Lactation Use

A-Phyline should not be used by women who are breast-feeding, as it may pass into breast milk and could potentially harm a nursing baby. If you are lactating, it is important to talk to your doctor about the risks of taking aminophylline.

Acute Overdose

An overdose of aminophylline can be serious and even fatal. Symptoms of an overdose include nausea, vomiting, rapid heartbeat, dizziness, seizures, and coma. If you or someone you know has taken an overdose of aminophylline, it is important to seek immediate medical attention.

Contraindication

A-Phyline is contraindicated in patients with known hypersensitivity to theophylline or to any component of the product. It should not be used in patients with severe heart failure or severe liver disease, as it can worsen these conditions.

Use Direction

A-Phyline should be taken only as directed by your doctor. Do not increase the dosage or take the medication more often than directed. Always take the medication with a full glass of liquid, and avoid taking it on an empty stomach.

Storage Condition

A-Phyline should be kept at room temperature, away from direct heat and light. Keep the medication out of reach of children and pets.

Volume Of Distribution

The volume of distribution of aminophylline is about 0.7 L/kg, which means that about 70% of the drug is distributed in the body. This volume changes depending on age, body size, and kidney function.

Half Life

The half-life of aminophylline is about 2 to 3 hours in adults, and can be longer in elderly patients or patients with impaired liver or kidney function. It may take up to 8 hours for the drug to be completely eliminated from the body.

Clearance

A-Phyline is cleared from the body mainly by the kidneys, but also by the liver, gastrointestinal tract, and lungs. The clearance rate is about 0.3 mL/hour/kg, and is affected by age, body size, and kidney function.

Here you find in details version of A-Phyline

Some Frequently Asked Questions About A-Phyline

What is A-Phyline?

A-Phyline is a prescription medicine used to treat wheezing, shortness of breath, tightness of chest caused by breathing problems such as asthma, bronchitis, emphysema and other lung diseases.

How does A-Phyline work?

A-Phyline works by relaxing and opening the muscles around the airways in the lungs. This helps to reduce wheezing and shortness of breath caused by asthma and other lung diseases.

What are the possible side effects of A-Phyline?

Common side effects of A-Phyline include nausea, vomiting, upset stomach, loss of appetite, headache, jitteriness, nervousness, confusion, dizziness, diarrhea, restlessness, and irregular heart beat.

Who should not take A-Phyline?

A-Phyline should not be used by people who are allergic to it, people with certain heart problems, people with overactive thyroid, people with it cytochrome P450 2E1(CYP2E1) deficiency, or people taking certain types of medications.

What should I tell my doctor before taking A-Phyline?

Tell your doctor about all medications you are taking, any medical conditions, allergies and all other important health facts before taking A-Phyline. You should also tell your doctor if you are pregnant or plan to become pregnant.

Is A-Phyline safe for pregnant women?

A-Phyline should not be used by pregnant women unless advised by their physician. If you are pregnant or plan to become pregnant, discuss your options with your doctor.

What should I avoid while taking A-Phyline?

You should avoid taking any other medications, herbal supplements, or vitamins while taking A-Phyline without consulting your doctor. You should also avoid drinking alcohol or smoking while taking A-Phyline.

What to do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take it as prescribed. Do not take two doses at once.

Can I take A-Phyline with other medications?

You should always tell your doctor about the medications you are currently taking before taking A-Phyline, as some medications can interact with A-Phyline. You should not take any other medications, herbal supplements, or vitamins while taking A-Phyline without consulting your doctor.

How long does A-Phyline take to work?

A-Phyline should start to work within one hour of taking it. The effects of the medication can last up to 8 hours.

What is the recommended dosage of A-Phyline?

The recommended dosage of A-Phyline is different depending on the age, weight and medical condition of the patient. The dosage is calculated by the doctor and should be followed as prescribed.

Is A-Phyline available over-the-counter?

No, A-Phyline is a prescription drug, therefore, it requires a prescription from a doctor and is not available over-the-counter.

Is A-Phyline habit forming?

No, A-Phyline is not habit forming. However, if you experience any side effects or symptoms of dependency, please consult your doctor immediately.

How long can I take A-Phyline for?

A-Phyline should only be taken for the duration prescribed by your doctor. Taking A-Phyline for longer than the duration prescribed can have serious side effects.

Is A-Phyline effective in treating asthma?

Yes, A-Phyline is effective in treating asthma. However, it is not a cure for asthma, and other medications may be prescribed for long-term relief.

What are the common signs of an allergic reaction to A-Phyline?

Common signs of an allergic reaction to A-Phyline include rash, itching or hives, swelling of the face, lips, or tongue, severe dizziness, trouble breathing or swallowing.

What are the storage instructions for A-Phyline?

A-Phyline should be stored at room temperature, out of reach of children and pets. Do not store in the refrigerator or freezer, and avoid exposure to direct sunlight and moist conditions.

What should I do in case of an overdose of A-Phyline?

In case of an overdose of A-Phyline, seek medical attention immediately. Symptoms of an overdose may include nausea, vomiting, dizziness, confusion, headache, rapid or irregular heartbeat, difficulty breathing, seizures, or coma.

What is the maximum daily dose of A-Phyline?

The maximum daily dose of A-Phyline is different for each person and depends on age, weight and medical condition. You should always follow your doctor’s instructions and do not exceed the recommended dose.

Is there any form of monitoring required for taking A-Phyline?

Your doctor may recommend monitoring of blood levels while taking A-Phyline to ensure the medication is at a therapeutic level in your system. Follow your doctor’s instructions and reports signs and symptoms to your doctor.

What are the long term effects of taking A-Phyline?

Long term use of A-Phyline can cause a decrease in kidney function, an increase in blood pressure, or a decrease in blood calcium levels. Monitor kidney function and other blood parameters closely while taking A-Phyline.

Should I take A-Phyline with food?

It is recommended to take A-Phyline with food. Taking the medication with food may help reduce the side effects such as stomach upset, nausea and vomiting.

Can I take A-Phyline if I am breastfeeding?

A-Phyline should be used only if prescribed by your doctor. You should discuss the risks and benefits of taking A-Phyline while breastfeeding with your doctor.

Can I take A-Phyline if I am pregnant?

A-Phyline should not be used by pregnant women unless advised by their physician. If you are pregnant or plan to become pregnant, discuss your options with your doctor.

Should I inform my employer that I am taking A-Phyline?

Yes. It is recommended that you inform your employer that you are taking A-Phyline as it may affect your ability to perform certain activities. Your doctor may also provide a letter or document stating your current health status and medications.

Will A-Phyline interact with other drugs?

Yes. A-Phyline may interact with other drugs and medications including over-the-counter drugs, herbal supplements, and other prescription drugs. Tell your doctor about all medications you are taking before taking A-Phyline.

Can I drink alcohol while I am taking A-Phyline?

No. You should avoid drinking alcohol or smoking while taking A-Phyline as it can increase the side effects of the medication.

Can A-Phyline be taken by children?

A-Phyline can be used to treat breathing problems in children, however, children should be monitored closely while taking A-Phyline. Speak to your doctor about the potential risks and benefits of using A-Phyline in children.

Can A-Phyline be used to treat COPD?

Yes, A-Phyline is often used to treat COPD (Chronic Obstructive Pulmonary Disease). It works by relaxing and opening the muscles around the airways to reduce wheezing and breathlessness.

Can I take A-Phyline before exercise?

Yes. A-Phyline may help increase your lung capacity and reduce the symptoms of asthma before exercise. Speak to your doctor about the risks and benefits of taking A-Phyline before exercise.

Are there any activities I should avoid while taking A-Phyline?

You should avoid activities that require alertness such as driving a car, operating heavy machinery and any activities that require mental concentration. Speak to your doctor for more information.

Are there any activities I should avoid while taking A-Phyline?

You should avoid activities that require alertness such as driving a car, operating heavy machinery and any activities that require mental concentration. Speak to your doctor for more information.

What is the most common side effect of A-Phyline?

The most common side effect of A-Phyline is upset stomach, nausea and vomiting. Other common side effects include headache, jitteriness, nervousness, confusion, dizziness, diarrhea, restlessness, and irregular heart beat.

Does A-Phyline interact with food?

No, A-Phyline does not interact with food. However, it is recommended to take A-Phyline with food as it may help reduce the side effects such as stomach upset, nausea and vomiting.

Can I crush or chew A-Phyline tablets?

No. A-Phyline tablets should only be taken as instructed by your doctor. Crushing, breaking or chewing tablets can reduce the effectiveness of the medication and can cause side effects.

Does A-Phyline treat the underlying cause of an allergic reaction?

No. A-Phyline will not treat the underlying cause of an allergic reaction. It helps to reduce the symptoms of an allergic reaction by relaxing and opening the airways in the lungs.

What are the long-term effects of taking A-Phyline?

Long term use of A-Phyline can cause a decrease in kidney function, an increase in blood pressure, or a decrease in blood calcium levels. Monitor kidney function and other blood parameters closely while taking A-Phyline.

Can I take A-Phyline with anti-inflammatory medications?

It is not recommended to take A-Phyline with anti-inflammatory medications as these medications can interact with each other and cause undesired side effects. Speak to your doctor for more information.

Can A-Phyline make it difficult to sleep?

Yes. A-Phyline may cause difficulty sleeping and restlessness. Taking the medication at bedtime may help reduce these side effects. Speak to your doctor for more information.

Will I need to continue taking A-Phyline if my symptoms improve?

Yes. It is important to continue taking the prescribed dose of A-Phyline even if your symptoms improve. Discontinuing the use of A-Phyline before the end of the prescribed duration can cause your symptoms to return.

Is there an age limit for taking A-Phyline?

No. A-Phyline can be used by adults and children above the age of 12 years old. Children should be monitored closely while taking A-Phyline. Speak to your doctor about using A-Phyline in children.